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Using 5-butylpicolinate esters improves the sensitivity and reliability of detecting testosterone and dihydrotestosterone in saliva.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Testosterone therapy can modestly improve sexual function in menopausal women but should be used cautiously and is not recommended for routine measurement in sexual dysfunction or hirsutism.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Phytoconstituents from Cyperus Rotundus may help treat hirsutism by interacting with the 5 α reductase enzyme.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Finasteride negatively affects fish reproduction and gonadal development.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.

5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.

Some vegetables from Northern Thailand show promise for health benefits, including hair loss treatment and antioxidant properties.

Testosterone reduces key molecules needed for early pregnancy in rats.

A new anti-baldness patch effectively treats hair loss by blocking enzymes linked to the condition.

Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.

Trazodone and chlorpromazine may help treat sexual dysfunction caused by finasteride and SSRIs.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

Androgens, like testosterone, are crucial for early testicular descent in rats.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.

Saw palmetto is an effective natural treatment for hair loss with minimal side effects.

Finasteride effectively treats hair loss in men with minimal side effects.

New treatments for male hypogonadism are effective and should be personalized.