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The research concluded that selection significantly shaped the genetic variation of the X chromosome, with certain regions affected by past selective events.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

The ITGB6 gene is important for tissue repair and hair growth, and mutations can lead to enamel defects and other health issues.

Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Male rats grow hair faster than females, and certain hormones can slow or slightly increase hair growth, but not significantly beyond natural rates.

Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.

Somatostatin may help protect hair follicles from immune attacks.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

Infertile men are more likely to produce sperm with abnormal chromosome numbers, which can affect pregnancy success and embryo health.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

L-Carnitine-L-tartrate may help hair grow and prevent hair loss.

Mobile phone radiation may cause DNA damage in human ear hair follicle cells.

Ozone therapy might improve cancer treatment and reduce its side effects.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

The HGCA tool helps identify genes that work together by analyzing their co-expression patterns.

The nafarelin test can reliably distinguish between gonadotropin deficiency and delayed puberty in teenage boys.

Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.

Benign Prostatic Hyperplasia may be caused by changes in how the body processes male hormones.

Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.