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Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.

Melatonin protects skin against UV damage by regulating various cellular processes.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.

Taking 5α-reductase inhibitors does not significantly increase the risk of breast cancer in men.

The normal human prostate does not significantly affect blood DHT levels.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Suppressing certain hormones might help prevent prostate cancer.

Finasteride temporarily lowers male rat fertility without affecting libido.

New compounds may soon be tested to treat excessive hair growth in women.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Reproductive gynecologists are the main referrers for male infertility evaluations in North America.

Certain gene variations are not a major cause of male infertility in Nigerian men.

Treatment during development affects hormone balance and sexual behavior in male rats.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

These drugs cause hair growth without affecting testosterone or adrenal hormones.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Castration and finasteride lower urinary oxalate in male rats, potentially treating urolithiasis.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

The review highlights the need for more research on transgender dermatology, the role of dermatologists in gender affirmation, and the effects of hormone therapy on skin and hair.

Delayed ejaculation is a complex issue caused by psychological, biological, and lifestyle factors, requiring a holistic treatment approach.