research The Biology and Clinical Application of Systemic Glucocorticoids
Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.
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research What Should It Take to Describe a Substance or Product as 'Sperm-Safe'?
Products should be called 'sperm-safe' only after thorough, well-designed tests.
research Classified Advertising
The document listed various medical job opportunities with competitive benefits and living conditions.
research Interpretation Of The Yak Skin Single-Cell Transcriptome Landscape
The study mapped yak skin cells to understand hair growth better.
research Table of Contents
research Tackling Underrepresentation to Aid Understanding of Parkinson’s Disease: Progress and Further Opportunities
Addressing underrepresentation in Parkinson's research is crucial for better treatments and understanding.
research Female Hyperandrogenism
The document concludes that managing female hyperandrogenism requires a combination of identifying the cause, lifestyle changes, medication, and cosmetic treatments.
research Recent Advances in Understanding and Managing Male Infertility
Losing weight, fixing varicoceles, and using advanced sperm selection methods improve male infertility treatment outcomes.
research Genetic Regulation of the Androgen Receptor: A Study of Testicular Feminization in the Mouse
The study concludes that a genetic mutation in TFM mice leads to reduced androgen receptor activity, affecting the body's response to male hormones.
research Anabolic Effect of Dihydrotestosterone in Testicular Feminization Syndrome
Dihydrotestosterone has a reduced effect on muscle-building in people with testicular feminization syndrome, especially after their gonads are removed.
research Indirect Clinical Markers for the Detection of Anabolic Steroid Abuse Beyond Conventional Doping Control in Athletes
New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.
research Characteristics of Finasteride Users in Comparison with Nonusers: A Nordic Nationwide Study Based on Individual-Level Data from Denmark, Finland, and Sweden
Finasteride users have higher odds of certain health issues and lower odds of specific lifestyle factors compared to nonusers.
research Association of 5-Alpha Reductase Inhibitors and Sexual Dysfunction: A RADAR Report
Using hair loss drugs finasteride and dutasteride may cause sexual side effects.
research Exposure of Xenopus Laevis Tadpoles to Finasteride, an Inhibitor of 5-Alpha Reductase Activity, Impairs Spermatogenesis and Alters Hypophyseal Feedback Mechanisms
Finasteride exposure harms tadpole reproduction and hormone balance.
research Finasteride
Finasteride caused serious side effects and led to six suicides.
research Normal Pubertal Development: Part II: Clinical Aspects of Puberty
Accurate assessment of puberty using Tanner staging is crucial for identifying normal and abnormal development.
research Relationship Between Betacoronaviruses and the Endocrine System: A New Key to Understand the COVID-19 Pandemic—A Comprehensive Review
Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.
research Testosterone Is a Contraceptive and Should Not Be Used in Men Who Desire Fertility
Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.
research Graham Little-Piccardi-Lassueur Syndrome Associated with Androgen Insensitivity Syndrome (Testicular Feminization)
A woman had both Graham Little-Piccardi-Lassueur syndrome, causing hair loss, and complete androgen insensitivity syndrome, making her genetically male but physically female. This suggests androgens don't affect the hair loss condition.
research Dihydrotestosterone and 5α-Reductase: Role in Hair Loss and Prostate Health
Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.
research Successful Virilization of a PAIS Patient with a Missense Mutation in the Ligand-Binding Domain of the Androgen Receptor Using Combined High-Dose Testosterone and Aromatase Inhibitor
A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.
research Physiological and Histological Study of the Effect of Finasteride Drug (Prostacare) on the Fertility of Albino Male Rats
Finasteride significantly reduces fertility in male rats.
research Faculty Opinions Recommendation of Androgenetic Alopecia Present in the Majority of Hospitalized COVID-19 Patients – The 'Gabrin Sign'
research Role of 5α-Reductase in Health and Disease
5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
research Case Report: A Study of the Clinical Characteristics and Genetic Variants of Post-Finasteride Syndrome Patients
Finasteride may cause lasting sexual and mental health issues, and genetic screening could help prevent them.
research Hair Restoration: Looking Beyond Minoxidil, Finasteride, and Hair Transplantation
Need better hair loss treatments beyond minoxidil, finasteride, and transplants.
research Notes from the Editor Emeritus: Coincidental Epigenetics or Post-Finasteride Syndrome?
The conclusion is that more research is needed to understand if the drug finasteride causes Post-Finasteride Syndrome or if it's due to individual genetic makeup.
research Unchanged Androgen-Binding Properties of Sex Hormone-Binding Globulin in Male Patients with Liver Cirrhosis
SHBG binding properties are unchanged in male liver cirrhosis patients.
research Preliminary Toxicity Profile of Arotinoids SMR-2 and SMR-6 in Male B6D2F1 Mice
SMR-2 and SMR-6 are much more toxic than retinoic acid, causing severe side effects.
research The Effect of Finasteride on the Secretion of Testosterone, DHT, LH, FSH, and Tissue Factors in the Testis of NMRI Mice
Finasteride reduces sperm count and quality and alters hormone levels in mice.