research Androgen Actions on the Human Hair Follicle: Perspectives
Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.
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research The Effects of Transdermal Dihydrotestosterone in the Aging Male: A Prospective, Randomized, Double-Blind Study
Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.
research Male Pattern Alopecia: A Histopathologic and Histochemical Study
Male pattern baldness involves smaller hair follicles, larger oil glands, and other tissue changes, but not major blood supply issues.
research Testosterone Supplementation for Aging-Associated Sarcopenia
Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.
research Congenital Adrenal Hyperplasia: A Comprehensive Review
The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.
research Persistent Sexual, Emotional, and Cognitive Impairment Post-Finasteride
Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.
research Emerging Medication for the Treatment of Male Hypogonadism
New treatments for male hypogonadism are effective and should be personalized.
research The E211 G>A Androgen Receptor Polymorphism Is Associated With a Decreased Risk of Metastatic Prostate Cancer and Androgenetic Alopecia
E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.
research Steroidogenesis of the Testis: New Genes and Pathways
New genes and pathways are important for testosterone production and male sexual development.
research Phenotypic Profiling of Parents With Cryptic Nonclassic Congenital Adrenal Hyperplasia: Findings in 145 Unrelated Families
Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.
research C-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis
The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.
research The Dihydrotestosterone Hypothesis of Prostate Cancer and Its Therapeutic Implications
The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
research Effects of Dermatological Medications on Male Fertility
Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.
research Men With Kennedy Disease Have a Reduced Risk of Androgenetic Alopecia
Men with Kennedy disease have less chance of hair loss.
research Leydig Cell Hyperplasia and Adenomas in Mice Treated with Finasteride, a 5α-Reductase Inhibitor: A Possible Mechanism
High doses of finasteride cause cell growth and tumors in mice.
research Safety Concerns Regarding 5α Reductase Inhibitors for the Treatment of Androgenetic Alopecia
5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.
research Current Evaluation of Amenorrhea
Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.
research Unchanged Androgen-Binding Properties of Sex Hormone-Binding Globulin in Male Patients with Liver Cirrhosis
SHBG binding properties are unchanged in male liver cirrhosis patients.
research The Molecular Basis of Androgen Insensitivity
Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.
research Current Evaluation of Amenorrhea
Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.
research Abnormal Essential Fatty Acid Composition of Tissue Lipids in Genetically Diabetic Mice Is Partially Corrected by Dietary Linoleic and Gamma-Linolenic Acids
Dietary essential fatty acids improved skin and hair conditions and partially corrected fat composition in diabetic mice.
research The Optimal Indication for Testosterone Replacement Therapy in Late-Onset Hypogonadism
Testosterone replacement therapy should be used for men with low testosterone levels and symptoms of hypogonadism, after careful diagnosis and considering individual needs.
research Synthesis and Biological Evaluation of Novel Unsaturated Carboxysteroids as Human 5α-Reductase Inhibitors: A Legitimate Approach
New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.
research Therapeutic Androgen Receptor Ligands
Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.
research Hormonal Regulation in Male Androgenetic Alopecia: Sex Hormones and Beyond - Evidence from Recent Genetic Studies
Hormones and genes affect hair growth and male baldness.
research Secondary Infertility Due to Use of Low-Dose Finasteride
Low-dose finasteride may cause fertility issues, but stopping it can improve sperm quality and lead to pregnancy.
research Lipid Levels in Women with Androgenetic Alopecia
Women with AGA have higher lipid levels, increasing heart disease risk.
research Male Fertility and Skin Diseases
Some skin diseases and their treatments can negatively affect male fertility.
research The Treatment of Acne
Early treatment of acne is important to prevent scarring and improve appearance, using medications that can have side effects.
research Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors
Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.