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Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Kennedy's disease leads to muscle weakness without a cure, but exercise and managing symptoms may help patients live a normal lifespan.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

Treat hair loss with finasteride, minoxidil, or surgery; consider side effects and severity.

Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Melatonin solution helps treat hair loss in men and women.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Early diagnosis and treatment are crucial for preventing permanent hair loss in various scalp conditions, and while new treatments are promising, more research is needed to evaluate their effectiveness.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

Finasteride reduces male rat fertility by causing issues with copulatory plug formation.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

A transwoman developed a brain tumor after nine years of hormone therapy, suggesting a possible link between the treatment and tumor development.

Iron deficiency is not a significant cause of hair loss in women.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Finasteride effectively treats male hair loss, improving growth and density.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Melatonin protects skin against UV damage by regulating various cellular processes.

Steroidogenic isoenzymes may help improve treatments for common hair loss.