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Finasteride effectively treats baldness but may cause sexual side effects.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

No single treatment is consistently effective for alopecia areata, and more research is needed.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

Finasteride may cause long-lasting sexual side effects.

Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Restoring hair bulb immune privilege is crucial for managing alopecia areata.

Minoxidil with propranolol and diuretics lowers blood pressure but causes fluid retention and hair growth.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Hair loss in men treated best with early medication or transplant, new treatments researched.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Spironolactone most effective for hirsutism, but has side effects.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.