research A Teenage Girl with Unexpected Pubertal Changes
The girl's unexpected pubic hair growth led to a diagnosis different from complete androgen insensitivity syndrome.
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research Tissue Engineering of the Reproductive System
Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.
research Identification of Ferroptosis-Related Biomarkers in Alopecia Areata Through Machine Learning
Four genes are potential markers for hair loss condition alopecia areata, linked to a specific type of cell death.
research Medical Care for Children and Adolescents with Gender Dysphoria and Gender Inconsistency in Light of Current Recommendations: How to Implement the 'Primum Non Nocere' Principle?
The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.
research Prepubertal Pattern Hair Loss
Children under 10 can experience hair thinning without hormone issues, and it may improve with treatment.
research A Preview of Selected Articles
New treatments for hair loss, fertility, and wound healing are being explored.
research 37-Year-Old Man With Fatigue and Erectile Dysfunction
The man's fatigue and erectile dysfunction were improved by treating his obesity-related low testosterone without needing testosterone replacement.
research Androgen Biosynthesis and Gene Defects
Gene mutations can cause problems in male genital development.
research 5α-Reductase Inhibitor Therapy: Should Physicians Be Concerned With Persistent Diminished Libido, Erectile Dysfunction, and Depression in a Subset of Patients?
Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.
research Table of Contents
The document covers various male health issues, their causes, treatments, and related conditions.
research Iatrogenic Male Infertility
Medical treatments like chemotherapy and radiotherapy can harm sperm production, so freezing sperm before treatment is important for men who want children later.
research Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice
Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
research The Effect of Finasteride in Men with Benign Prostatic Hyperplasia
Finasteride effectively treats BPH but may increase sexual dysfunction risk.
research The Cutaneous Serotoninergic/Melatoninergic System: Securing a Place Under the Sun
Human skin can make serotonin and melatonin, which help protect and maintain it.
research 5α-Reductase Activity in the Prostate
Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.
research The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases
The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
research Androgen Receptor Antagonists Structure-Activity Relationships
Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.
research The Effect of 5α-Reductase Inhibition with Dutasteride and Finasteride on Semen Parameters and Serum Hormones in Healthy Men
Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.
research Fortnightly Review: Male Pattern Androgenetic Alopecia
Hair loss in men is common, treatable, but not curable.
research The Hair Follicle as an Estrogen Target and Source
Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
research Androgens and Human Hair Growth
Androgens can cause hair growth in some areas and hair loss on the scalp.
research Linking Diet to Acne Metabolomics, Inflammation, and Comedogenesis: An Update
Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.
research The Role of Androgen and Androgen Receptor in Skin-Related Disorders
Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.
research Clinical Management of Youth with Gender Dysphoria in Vancouver
Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.
research Persistent Sexual Side Effects of Finasteride: Could They Be Permanent?
Finasteride may cause long-lasting sexual side effects.
research Testosterone and Doping Control
The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.
research Hair Follicle Immune Privilege Revisited: The Key to Alopecia Areata Management
Restoring hair bulb immune privilege is crucial for managing alopecia areata.
research Androgens and Androgen Receptor Action in Skin and Hair Follicles
Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.
research Hormonal Regulation of Hair Follicles Exhibits a Biological Paradox
Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.
research Diagnosis and Management of the Dermatologic Manifestations of Polycystic Ovary Syndrome
The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.