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Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Cancer therapy can cause various skin problems, including hair loss, skin darkening, painful hand-foot syndrome, and severe skin damage.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Finasteride may cause long-lasting sexual side effects.

Minoxidil and finasteride can slow hair loss and stimulate regrowth, but won't restore all lost hair or reverse complete baldness.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Lowering testosterone speeds up wound healing in male mice.

Finasteride doesn't harm male fertility or sperm quality, but may slightly reduce ejaculate volume.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Restoring hair bulb immune privilege is crucial for managing alopecia areata.

Minoxidil with propranolol and diuretics lowers blood pressure but causes fluid retention and hair growth.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Hair loss in men treated best with early medication or transplant, new treatments researched.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Spironolactone most effective for hirsutism, but has side effects.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.