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5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

A transwoman developed a brain tumor after nine years of hormone therapy, suggesting a possible link between the treatment and tumor development.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Finasteride and minoxidil together work best for male hair loss.

Hair restoration surgery has advanced, focusing on natural results and may improve further with new techniques and therapies.

Finasteride effectively treats male hair loss, improving growth and density.

Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.

Melatonin protects skin against UV damage by regulating various cellular processes.

LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.

Most hair loss in children is caused by a few common conditions, and it's important to diagnose these properly and support the child's mental health.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.

Ketoconazole shampoo with finasteride improves hair density in men with hair loss.

The normal human prostate does not significantly affect blood DHT levels.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

Finasteride temporarily lowers male rat fertility without affecting libido.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Finasteride cream reduces hair growth in women with hirsutism, but more research needed.