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Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

People with late-stage HIV-1 often experience a specific type of hair loss linked to multiple factors, including nutritional issues and immune responses.

Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

Treat hair loss with finasteride, minoxidil, or surgery; consider side effects and severity.

Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.

Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.

Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Melatonin solution helps treat hair loss in men and women.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Hormones, nutrition, and seasonal changes regulate hair growth cycles, with androgens extending growth phases and factors like aging and malnutrition affecting hair loss and thinning.

Early diagnosis and treatment are crucial for preventing permanent hair loss in various scalp conditions, and while new treatments are promising, more research is needed to evaluate their effectiveness.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

Finasteride reduces male rat fertility by causing issues with copulatory plug formation.

5-alpha-reductase inhibitors may reduce COVID-19 symptoms in bald males.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

A male with aromatase deficiency improved bone health with estradiol treatment.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.