research Effect of Testosterone, Dihydrotestosterone, Estradiol, and Cortisol on the Quality of Fresh and Cryopreserved Stallion Sperm
Higher testosterone harms sperm motility, while higher estradiol improves sperm survival.
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research Testosterone Deficiency Is Not Protective Against the Development of Adenocarcinoma of the Prostate in a Type 1 Diabetic Patient
Low testosterone does not prevent prostate cancer in men with type 1 diabetes.
research The Role of Testosterone in SARS-CoV-2 Infection
Low testosterone levels may lead to more severe COVID-19 outcomes.
research Serum Testosterone Levels and Clinical Signs of Hypogonadism in Men with Type 2 Diabetes
Men with type 2 diabetes often have low testosterone and signs of hypogonadism, especially if they are overweight.
research Mechanisms of Testosterone Action
Testosterone works in different ways, including direct interaction with its receptor, conversion to other hormones for specific effects on genitalia, hair, bones, and muscle, and changes in body fat and sexual function when low.
research Intracrine Testosterone Activation in Human Pancreatic Beta Cells Stimulates Insulin Secretion
Testosterone in our bodies helps increase insulin secretion from the pancreas.
research Intracrine Testosterone Activation in Human Pancreatic Beta Cells Stimulates Insulin Secretion
Testosterone in human pancreas cells boosts insulin production.
research Decision Letter: Effects of Lifelong Testosterone Exposure on Health and Disease Using Mendelian Randomization
Increased free testosterone can lead to stronger bones and less body fat but also higher risks of prostate cancer, hair loss, spine issues, and high blood pressure.
research FDA-Approved (Bremelanotide, Flibanserin) and Off-Label Medications (Testosterone, Sildenafil) to Enhance Sexual Desire and Function in Women
Some medications can help increase sexual desire and function in women.
research Testosterone Secreting Ovarian Tumor: A Rare Cause of Erythrocytosis and Pulmonary Embolus
A rare ovarian tumor that produced testosterone caused a blood clot in the lungs and increased red blood cells in a woman.
research Elevated Testosterone Secondary to Leydig Cell Hyperplasia in Bilateral Ovaries
A woman's high testosterone and related symptoms were caused by overactive cells in her ovaries.
research Male Pattern Baldness and Waist-Hip Ratio as Markers of Arterial Stiffness in Transgender Men Undergoing Long-Term Testosterone Therapy
Male pattern baldness may indicate arterial stiffness in transgender men on long-term testosterone therapy.
research Protective Effect of Ellagic Acid on Testosterone-Induced Alopecia in Rats
Ellagic acid may help prevent hair loss caused by testosterone in rats.
research Effect of High Levels of Testosterone on Cardiovascular Risk in Polycystic Ovary Syndrome
High testosterone increases heart disease risk in women with PCOS.
research The Effect of Laparoscopic Ovarian Drilling on the Serum Levels of AMH, FSH, LH, and Testosterone Hormones in Patients with PCOS
Laparoscopic ovarian drilling helps infertile women with PCOS by improving menstrual regularity, ovulation, and chances of conception, and by changing hormone levels.
research Behavior of the Two Circulating Androgens Testosterone and DHEA and Their Main Intracellular Metabolites in an Androgen-Sensitive Sebocyte Cell Line
Testosterone affects androgen receptors and lipid storage in cells, while DHEA does not convert to testosterone or affect these receptors in the same way.
research Falsely Elevated Testosterone Levels: Role of LC-MS/MS in Reducing Unnecessary Testing
Using LC-MS/MS for hormone measurement can prevent false high testosterone results and avoid unnecessary tests.
research Novel Presentation of a Heterozygous INSR Mutation and Markedly Elevated Testosterone Levels in a Pediatric Patient: A Case Report
A young patient with unusual insulin resistance and high testosterone levels had a rare INSR gene mutation.
research Ovaries Reveal Their Inner Testes: A Case of Tumorous Hyperandrogenism
A woman's severe male-like symptoms were caused by a rare, benign tumor in her ovary that produced male hormones.
research Successful Virilization of a PAIS Patient with a Missense Mutation in the Ligand-Binding Domain of the Androgen Receptor Using Combined High-Dose Testosterone and Aromatase Inhibitor
A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.
research Telogen Effluvium on the Unilateral Flank with Testicular Tumor in a Dog
A dog's hair loss was caused by a hormone-secreting testicular tumor.
research Evaluation of Low Testosterone Levels in Male Dogs with Alopecia
Low testosterone might be a common cause of hair loss in male dogs.
research Relationship Between Glucose Homeostatic Disorders and Testosterone in Adult Nigerian Women With Polycystic Ovary Syndrome
Higher testosterone levels in Nigerian women with PCOS are linked to glucose disorders like diabetes.
research Clomiphene Citrate and Human Chorionic Gonadotropin Are Both Effective in Restoring Testosterone in Hypogonadism: A Short-Course Randomized Study
Clomiphene citrate is a cheap and simple treatment for low testosterone that works as well as human chorionic gonadotropin, alone or combined, especially for men who want to keep their fertility.
research Clinical Improvements in Erectile Function and Mood in Hypogonadal Men Treated with 4.5% Nasal Testosterone Gel (Natesto)
Natesto nasal gel improves erectile function and mood in men with low testosterone within 30 days.
research Possible Association Between Androgenic Alopecia and Risk of Prostate Cancer and Testicular Germ Cell Tumor: A Systematic Review and Meta-Analysis
There might be a link between male pattern baldness and a higher risk of prostate cancer and testicular cancer.
research Protective Effect of DA-9401 in Finasteride-Induced Apoptosis in Rat Testis: Inositol Requiring Kinase 1 and c-Jun N-Terminal Kinase Pathway
DA-9401 can protect against finasteride-induced reproductive damage in rats.
research Prostaglandin D2 Enhances Testosterone Metabolism by ROS-Mediated Altered Redox Potential in Keratinocytes
Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.
research Testosterone Is Poorly Related to Erectile Dysfunction in Young and Middle-Aged HIV-Infected Men
Testosterone levels are not linked to erectile dysfunction in young and middle-aged men with HIV.
research Investigating the Mechanisms Underlying Effects of Testosterone on Blood Pressure in Normotensive and Hypertensive Rats
Testosterone raises blood pressure by affecting kidney function and brain gene regulation over time.