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The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.

pCLCA2 protein may help maintain skin structure and function.

Different types of stem cells and their environments are key to skin repair and maintenance.

Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Keratins are important for skin cell health and their problems can cause diseases.

Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.

Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.

Psoriasis lesions have fewer and smaller oil glands, which might affect the condition's development.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

The circadian clock influences the behavior and regeneration of stem cells in the body.

The research identified genes that explain why some sheep have curly wool and others have straight wool.

Newer retinoid drugs are effective for skin conditions but have significant side effects.

Intermediate filaments are crucial for cell differentiation and stem cell function.

Hair follicle stem cells are promising for wound healing but require more research for safe clinical use.

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

The calcineurin/NFAT pathway plays a significant role in the development and growth of a type of skin cancer called cutaneous squamous cell carcinoma.

CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.

Chemotherapy damages hair follicles, causing hair loss and other cellular changes.

Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

Retinoic acid helps change skin cells and is important for skin development and hair growth.

Activating c-Myc in skin causes rapid cell growth and changes, but these effects are reversible.

Notch signaling disruptions can cause various skin diseases.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.