2 citations
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January 2018 in “International Journal of Advanced Community Medicine” This study reported the formulation of a new cream combining niacinamide and retinol aimed at reducing hyperpigmentation and providing anti-aging and moisturizing effects. It found that the cream remained stable under various environmental conditions and did not cause skin irritation in patch tests.
1 citations
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December 2016 This computational study developed a regulatory model linking key genes and miRNAs to cardiac senescence, validated by connecting 94% of these elements to existing cardiac aging research.
1 citations
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December 2005 in “Therapeutische Umschau” This article reviews anti-aging strategies in dermatology, emphasizing the role of skin as a model for studying aging and promoting preventive and therapeutic interventions, but it does not present new findings.
April 2026 in “Dermatology and Therapy” This Delphi consensus study provides expert insights into hair aging, aims to enhance diagnostic precision and management of age-related hair changes, and identifies possible new therapeutic targets.
February 2026 in “Journal of Regenerative Medicine and Biology Research” This study explores the potential roles of exosomes in anti-aging applications, highlighting their ability to modulate inflammation, promote tissue regeneration, and transfer bioactive molecules to rejuvenate aging tissues and reverse cellular dysfunction.
March 2025 in “International Journal of Pharmaceutical Research and Applications” This study highlights recent biological and technological strategies in anti-aging research aimed at delaying aging and related diseases, improving skin healing, and potentially restoring hair growth.
This study suggests that bioactives like Curcumin, Quercetin, and "Tulsi" may relieve chemotherapy-induced adverse drug reactions in cancer patients, potentially reducing resistance and recurrence.
33 citations
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January 2021 in “Aesthetic Surgery Journal” This review suggested that low-level light therapy using red/near-infrared light could be a safe and effective treatment for various skin and hair conditions, though more robust trials are needed to solidify its clinical utility.
23 citations
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August 2018 in “Facial Plastic Surgery Clinics of North America” This review discusses the role of defensin peptides in stem cell activation for potential skin rejuvenation therapies and reports no new clinical findings, emphasizing the need for further studies.
11 citations
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January 2013 in “Postępy Dermatologii i Alergologii” This review discusses various theories of skin aging and the importance of using professional and at-home skincare solutions, but offers no new empirical findings.
3 citations
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October 2007 in “Expert Review of Dermatology” This review discusses the biological and cosmetic aspects of hair aging and reports no new clinical results; it highlights current treatments and future research directions to address both aging factors.
59 citations
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November 2010 in “Circulation Research” This review discusses the potential role of Wnt signaling in aging-related heart diseases and reports no clinical results.
September 2013 in “Molecular Biology” This study found that Satura Rosta Balm exerts a cytotoxic effect under oxidative stress and may trigger regeneration through autophagic pathways, despite not promoting proliferation or stress resistance in human cells.
293 citations
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November 2011 in “Nature” This study found that the circadian clock regulates the activation state of murine epidermal stem cells, affecting tissue homeostasis and susceptibility to tumorigenesis when disrupted.
172 citations
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May 2018 in “Nature” Mammalian organs regenerate using stem cells and cell plasticity, but this ability declines with age.
143 citations
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September 2008 in “Experimental gerontology” This review discusses the diverse roles and characteristics of epidermal and dermal stem cells in skin regeneration and aging, highlighting their potential applications in regenerative medicine and reports no new clinical results.
138 citations
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June 2019 in “Stem Cells and Development” This review explores the potential of periodontal ligament stem cells for regenerative therapy in periodontium, despite challenges due to their rarity, and reports no clinical results.
133 citations
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September 2013 in “Nature Reviews Molecular Cell Biology” Different types of stem cells and their environments are key to skin repair and maintenance.
68 citations
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September 2018 in “International Journal of Molecular Sciences” In this study, researchers found that exposure to PM10 significantly increased inflammation and impaired collagen synthesis in human dermal fibroblasts, suggesting PM10 contributes to skin aging through these mechanisms.
61 citations
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September 2010 in “Genomics” This study found distinct gene expression profiles in alopecia areata-affected skin, suggesting T-cell mediated immune responses and unique gene profiles between different stages of the disease.
60 citations
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January 2023 in “Biogerontology” This review examines testosterone's role in male health and aging but reports no new clinical results; the authors highlight the need for further research on optimal testosterone levels to prevent age-related conditions.
42 citations
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April 2009 in “Human Genetics” This study suggests that the AGA risk haplotype in Europeans was driven to high frequency by positive selection, likely associated with a variant in the EDA2R gene.
41 citations
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December 2018 in “Experimental Dermatology” This review explores recent findings on the roles of melanocyte and melanocyte stem cells in the hair follicle, highlighting their importance for skin health and potential applications in regenerative medicine, but reports no new clinical results.
36 citations
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August 2011 in “Journal of Controlled Release” This review explores the potential of using genetically-manipulated stem cells as both therapeutic agents and gene delivery vehicles for enhanced wound regeneration, but it reports no new clinical results.
32 citations
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August 2019 in “Nature Communications” In this study, researchers found that alkylating chemotherapy causes hair follicle stem cells to lose their regenerative ability by initially triggering proliferation followed by apoptosis, leading to permanent regeneration loss.
30 citations
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April 2010 in “Cell Cycle” This review discusses how the p53 tumor suppressor gene helps maintain adult tissue homeostasis by promoting the removal of DNA-damaged cells, with implications for treating age-related diseases and p53-deficient cancers; it reports no new results.
25 citations
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March 2012 in “Journal of Dermatological Science” This review discusses genome-wide association studies in dermatology, noting that variants linked to risk for 10 skin complex diseases have been identified, with potential implications for diagnostics and management; it reports no new clinical results.
22 citations
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November 2024 in “Planta” This review highlights the potential of aromatic plants as natural antioxidants in cosmeceuticals, which may combat skin aging and promote rejuvenation by counteracting oxidative stress, offering a natural alternative to synthetic products with benefits like photoprotection and anti-wrinkle effects.
22 citations
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November 2012 in “Journal of cosmetic dermatology” This review outlines the processes and potential of stem cells in regenerating skin, hair, and other tissues but presents no new experimental findings.
18 citations
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January 2017 in “Dermatologic Surgery” This review examines intrinsic and extrinsic aging impacts and presents evidence-based lifestyle recommendations to complement cosmetic procedures for enhanced antiaging outcomes, but it reports no new clinical results.