Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In a depilated mouse model, this study found that blocking CXCL4 activity with an anti-CXCL4 monoclonal antibody promoted hair growth by inducing an earlier anagen phase, delaying hair follicle regression, and altering expression of genes and proteins related to hair growth and cell proliferation.

The authors concluded that chronic telogen effluvium in middle-aged women presents distinct clinical and histological features that differ from androgenetic alopecia and acute telogen effluvium.

In this study, RNA-Seq analysis identified 2717 genes differentially expressed between anagen and telogen hair follicle stem cells in cashmere goats, potentially involving several signaling pathways in vitro.

This study observed that vellus hairs and empty spaces are present in prepubertal children's scalps, but they likely do not indicate androgenetic alopecia, suggesting a natural 'true resting' phase of scalp hair.

This study found that a topical treatment combining arginine and zinc significantly reduced hair loss and increased anagen hair percentage in patients with androgenetic alopecia and telogen effluvium, suggesting it might be a promising alternative to finasteride.

This clinical trial found that Sandalore® 1% significantly reduced hair shedding and increased hair volume and anagen hair follicles in women with telogen effluvium compared to placebo.

This review proposes a new classification for telogen effluvium, identifying three pathogenetic types with a common feature of profuse hair shedding, but reports no new clinical results.

This study demonstrated that topical oleuropein induced hair growth in mice by activating the Wnt10b/β-catenin signaling pathway and increasing expression of several growth-related genes in skin tissue.

This study found that intradermal adipocyte lineage cells in mice are necessary and sufficient to activate follicular stem cells, highlighting their role in regulating skin stem cell activity.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

This article reviews the role of epithelial-mesenchymal interactions in hair follicle morphogenesis and the hair cycle, suggesting potential paths for developing treatments for hair growth disorders but providing no new clinical findings.

This article discusses the influence of estrogens on hair follicle growth and metabolism, suggesting a significant role alongside androgens in hair growth control but reports no new clinical results.

In this study, Msx2-deficient mice showed progressive hair loss due to shortened anagen phase and prolonged catagen and telogen phases, resulting in cyclic alopecia with structurally abnormal hair shafts.

This article discusses the structure of hair follicles and their significance in evaluating hair disorders, but it does not report any new research findings.

This study found that low fluence photoepilation with intense pulsed light targets the pigmented area of hair follicles, causing temporary hair loss by inducing a catagen-like state without severe follicle damage.

In this study, researchers found that bulge cells in mouse hair follicles undergo transient proliferation during early anagen, indicating their role as follicular stem cells. However, another factor beyond dermal papilla proximity may be required to initiate a new anagen phase.

This study identified potential ceRNA regulatory networks in cashmere goat hair follicle cycling, expanding understanding of lncRNA and miRNA biology and annotation of the goat genome.

This study found that finasteride increases anagen hair growth in men with androgenetic alopecia.

This study found that the methanol extract of Eclipta alba showed dose-dependent hair growth promoting activity in pigmented C57/BL6 mice by influencing the transition from the telogen to anagen phase.

This study found that anagen-phase hair follicles in mice are particularly sensitive to damage by ruby laser pulses, resulting in alopecia without scarring, suggesting enhanced laser hair removal strategies.

This review discusses the hair follicle cycle's complex regulation and highlights the potential for targeting catagen control in future therapies without presenting new experimental data.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

This study defines classification criteria for hair follicle dystrophy using a mouse model of chemotherapy-induced alopecia, providing tools for standardized hair damage assessment.

This study found that PGF2alpha analogues and PGE2 stimulated hair follicle activity in mice, with PGF2alpha analogues also linked to potential side effects like poliosis when used as eye treatments.

This study observed that vitamin D receptor expression in certain hair follicle cells varies throughout the murine hair cycle, suggesting a potential role for 1,25-dihydroxyvitamin D3 in hair follicle biology.

This study found that prolactin and its receptor are expressed in the murine hair follicle epithelium, influencing hair cycle phases by down-regulating keratinocyte proliferation during anagen and inducing premature catagen.

This study found that individuals with androgenic alopecia have an increased number of thin hairs (less than 40 microns in diameter) per cm², which may affect their clinical appearance.

This review outlines the classification, histopathologic presentation, and pathogenetic concepts of scarring and nonscarring alopecias, reporting no new clinical results and emphasizing the need for clinicopathologic correlation.

This study found that activating autophagy with specific small molecules and drugs can stimulate hair growth by initiating the anagen phase in dormant hair follicles, suggesting a potential treatment for hair loss.

This study observed that melanogenesis in human hair follicles is linked to anagen phases, with melanocyte activity and enzyme expression being region-specific to the nascent bulb.