Dermal stem cells help regenerate hair follicles and heal skin wounds.
30 citations,
May 2018 in “Experimental Dermatology” The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.
6 citations,
January 2020 in “Skin Pharmacology and Physiology” HIF-1α stimulators, like deferiprone, work as well as popular hair loss treatments, minoxidil and caffeine, in promoting hair growth.
254 citations,
January 2012 in “Nature Reviews Molecular Cell Biology” Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
43 citations,
February 2019 in “International immunology” Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.
27 citations,
December 2016 in “Dermatology and Therapy” Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.
13 citations,
July 2022 in “Frontiers in cell and developmental biology” Tiny natural vesicles from cells might help treat hair loss.
14 citations,
October 2020 in “Natural Products and Bioprospecting” Various treatments, including FDA-approved drugs, natural products, and oral supplements, can help with hair loss, but a patient's medical history and potential allergies should be considered when choosing a treatment.
52 citations,
September 2018 in “International Journal of Molecular Sciences” Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.
10 citations,
January 2003 in “Seminars in reproductive medicine” The article explains how to identify and treat excessive hair growth in women, which can be distressing and may signal other health problems.
271 citations,
September 2008 in “Nutrition reviews” Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.
112 citations,
January 2014 in “Molecular and cellular therapies” Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
18 citations,
October 2018 in “Nutrients” Annurca apple extract promotes hair growth by changing hair follicle metabolism to boost keratin production.
6 citations,
May 2013 in “PloS one” The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.
4 citations,
April 2020 in “Facial Plastic Surgery Clinics of North America” Hair loss in women is complex to diagnose and treat, and hair restoration should be done by experts. Using minoxidil before surgery can help manage post-surgery hair shock loss. The Follicular Unit Transplantation method is recommended for women due to its speed, no need for shaving, and better graft quality. Strategies like L, T, and reverse L patterns can help restore central hair density, and regenerative methods can improve graft survival in hair transplants.
There are many treatments for common hair loss, but more trials are needed to decide which are best.
33 citations,
November 2006 in “Survey of Ophthalmology” Madarosis is the loss of eyelashes and eyebrows due to various health issues and requires thorough examination to diagnose and treat the underlying cause.
1 citations,
May 2017 in “InTech eBooks” Some cosmetic procedures show promise for treating hair loss, but more research is needed to confirm their safety and effectiveness.
110 citations,
July 2017 in “Immunology” Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.
39 citations,
September 2013 in “Journal of Cosmetic Dermatology” Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.
66 citations,
July 2015 in “Journal of Molecular Biology” The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
61 citations,
December 2016 in “The EMBO Journal” The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.
18 citations,
November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
10 citations,
June 2019 in “International Journal of Cosmetic Science” Some plant-based chemicals may help with hair growth, but more research is needed to confirm their effectiveness.
6 citations,
November 2020 in “Molecular and Cellular Endocrinology” Androgens reduce BMP2, which weakens the ability of certain cells to help hair stem cells become different types of cells.
223 citations,
January 2014 in “International Journal of Molecular Sciences” The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.
52 citations,
October 2012 in “Journal of Dermatological Science” The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
29 citations,
December 2012 in “Fibrogenesis & Tissue Repair” Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.
January 2008 in “Springer eBooks” Thyroid disease can cause hair loss and treating thyroid problems might help with hair disorders.
January 2006 in “The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology” Rubus coreanum may help hair growth but not through the tested mechanisms, and none of the herbal extracts help with acne.