8 citations
,
August 2014 in “Clinical and Experimental Dermatology” This study found that chronic telogen effluvium is a distinct condition from female pattern hair loss, with different pathogenic mechanisms observed in histomorphometric analyses.
16 citations
,
February 2001 in “PubMed” This study found that allergic contact dermatitis of the scalp may cause telogen effluvium, leading to mild to moderate hair loss in some patients.
October 2005 in “CRC Press eBooks” Telogen effluvium is a condition where hair falls out due to various factors like illness, stress, or nutrient deficiency.
69 citations
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March 1993 in “Archives of Dermatology” This article proposes five mechanisms for telogen effluvium based on changes in the follicular cycle, which are supported by clinical findings, highlighting the condition's diverse causes.
November 2001 in “CRC Press eBooks” This article discusses how metabolic imbalances can trigger telogen effluvium by causing hair follicles to prematurely enter the shedding phase, and includes no new research findings.
35 citations
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July 2018 in “Cell Reports” This study found that the dermal papilla of the hair follicle regulates stem cell quiescence and regeneration by modulating Shh and Wnt signaling pathways, highlighting the importance of signaling cross talk in regeneration.
January 2011 in “China Animal Husbandry & Veterinary Medicine” This study examined the effects of constant-release melatonin on the SOX21 gene in Inner Mongolia Cashmere goats, finding that it stabilized gene expression and reduced stress responses with notable expression changes except in March, April, and May.
February 2024 in “Biomedicines” This review examines the hormonal causes of hair loss, noting how androgen excess can lead to follicle miniaturization and linking estrogen deficiency and thyroid dysfunction to common alopecia types. It further discusses hormonal treatments such as finasteride, dutasteride, and spironolactone.
4 citations
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December 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This article discusses the role of human scalp hair follicles in neurohormone production and their model potential for studying neuroendocrine signaling, reporting no experimental results.
2 citations
,
February 2024 in “Toxins” This study found that bee venom accelerated the transition from the telogen to anagen phase in mice, increasing hair growth by day 14, and suggested that bee venom may enhance adipose-derived stem cell activity by upregulating growth factor secretion.
81 citations
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April 2009 in “Journal of Investigative Dermatology” This review discusses the shedding phase of the hair cycle, known as exogen, and reports no new findings while analyzing related processes like club fiber formation and release.
This review highlights that microtrauma, involving small intentional skin injuries, shows promise in stimulating hair growth in non-scarring alopecias by enhancing immune responses and increasing growth factor release, with methods like microneedling and PRP demonstrating efficacy.
January 2024 in “Turkiye Klinikleri Journal of Dermatology” This review discusses the potential of microneedling as a treatment for hair loss, suggesting it may stimulate hair growth through controlled skin trauma and growth factor release, but notes clinical data are limited and lacks standardized procedures.
This review explores the connection between COVID-19 infection and telogen effluvium, highlighting the potential contribution of inflammatory and emotional factors to hair loss; it reports no clinical results.
28 citations
,
January 2021 in “Skin appendage disorders” This study observed that telogen effluvium, or acute hair loss, often occurs 1 to 3 months after SARS-CoV-2 infection, earlier than classic telogen effluvium.
1 citations
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December 2022 in “PubMed” This article reviews the potential causes of post-COVID telogen effluvium, attributing it to both inflammatory responses to SARS-CoV-2 and psychosocial stress, and suggests that hair recovery may occur without specific treatment.
July 2022 in “Journal of Investigative Dermatology” This study found that Substance P increased mitochondrial activity and biogenesis markers in cultured human scalp hair follicles, suggesting a novel link between stress-related neuropeptide signaling and hair follicle mitochondrial responses.
7 citations
,
October 2000 in “Allergo Journal” Stress may affect hair growth by influencing hair follicle development and could contribute to hair loss.
27 citations
,
September 2015 in “Drug Design Development and Therapy” This study suggests that type IV collagenases, MMP-2 and MMP-9, play important roles in the hair cycle by regulating the expression of VEGF, IGF-1, and TGF-β in mice.
26 citations
,
December 2015 in “International Journal of Dermatology” This abstract reviews the symptom of trichodynia, a painful scalp sensation linked to hair loss, and highlights its potential connection to inflammation but reports no new research findings.
7 citations
,
July 2022 in “Pharmaceutics” This study found that a dissolvable microneedle device delivering rapamycin and epigallocatechin gallate nanoparticles significantly enhanced hair regrowth in C57BL/6 mice within 7 days, demonstrating increased hair shaft growth and follicle density with minimal inflammation compared to untreated mice.
7 citations
,
July 2019 in “International Journal of Molecular Sciences” This study found that PGA-4HGF nanoparticles enhanced hair growth in mice more effectively than 4HGF alone by increasing anagen phase duration and dermal papilla cell proliferation.
4 citations
,
January 2021 in “Skin appendage disorders” This review discusses hair straightening techniques, products, and safety risks, providing guidance for dermatologists to advise patients effectively; it reports no new clinical results.
3 citations
,
August 2019 in “Journal of The American Academy of Dermatology” This study found that platelet-rich plasma with microneedling for hair loss was mostly well tolerated, but some patients experienced mild side effects like scalp itching, transient hair shedding, and lymphadenopathy.
July 2026 in “International Journal of Drug Delivery Technology” This research reported that liposomal systems made from pig-derived skin lipids enhanced finasteride delivery to hair follicles for treating androgenetic alopecia, showing improved drug deposition, hair length, and growth compared to conventional finasteride forms in vitro.
November 2008 in “Medical & surgical dermatology” This study reports that a prototype device may accurately measure changes in hair quantity, diameter, and density in patients with balding by assessing the cross-sectional area of hair bundles.
January 2000 in “Proyectar La Rioja” This study reports that telogen effluvium, a type of hair thinning, commonly follows SARS-CoV-2 infection after 1 to 3 months, possibly due to stress, inflammation, or direct viral impact on hair follicles.
November 2025 in “SKIN The Journal of Cutaneous Medicine” This review highlights the potential benefits of low-level light therapy for treating various alopecias, with reported improvements in hair density and count, especially when combined with minoxidil or finasteride, but it offers no new clinical results.
December 2022 in “Journal of Education, Health and Sport” This review suggests that combining treatments such as oral supplements, topical minoxidil, and high-platelet plasma may be effective for addressing telogen effluvium after COVID-19 infection, which affects about 30% of patients.
2 citations
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January 2023 in “BioMed Research International” The researchers reported that a 5% Beta vulgaris L. extract nanogel showed better antialopecic activity in testosterone-induced alopecia in mice compared to a 2.5% concentration.