1 citations
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June 1999 in “American Journal of Contact Dermatitis” In this study, tazarotene 0.1% gel showed greater efficacy than tretinoin 0.025% gel in reducing acne lesions and demonstrated similar efficacy to adapalene 0.1% gel when used less frequently.
19 citations
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January 2023 in “ACS Omega” This study developed sodium alginate and epigallocatechin gallate cryogels cross-linked with ferric ions, showing that they have strong antibacterial properties and rapid hemostatic abilities, making them promising candidates for wound dressing applications.
78 citations
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February 2024 in “ACS Omega” This study developed a bilayer material combining poly(vinyl alcohol) and bacterial cellulose with a gelatin-poly(vinyl alcohol) hydrogel, showing strong potential as a wound dressing due to its good antibacterial properties, cell viability, and sustained drug release.
22 citations
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October 2024 in “Advanced Healthcare Materials” This study demonstrated that gelatine-based hydrogel foams loaded with platelet extracellular vesicles (pEVs) promoted full wound closure in a chronic wound rat model within 14 days, suggesting potential for personalized treatment of chronic diabetic wounds.
48 citations
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February 2025 in “Advanced Materials” This study found that a glucose-activated hydrogel significantly improved chronic diabetic wound healing by regulating blood glucose and enhancing the wound microenvironment, achieving a threefold increase in recovery rate compared to commercial dressings.
83 citations
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May 2021 in “Biomolecules” This study found that an injectable composite hydrogel containing cerium bioactive glass improved wound healing in diabetic rats by promoting angiogenesis and offering antibacterial properties, suggesting its potential for enhancing diabetic foot wound repair.
April 2026 in “JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA” In this study, the researchers successfully developed a Spanlastic gel containing EGCG for transdermal application, significantly increasing EGCG skin permeability with optimal entrapment efficiency, zeta potential, and vesicle size.
September 2025 in “Acta Biomaterialia” In this study, researchers developed injectable micropore-forming hydrogels that enhance tissue adhesion strength and promote wound healing by allowing better cell infiltration and inducing hair follicle regeneration in skin incision wound models.
11 citations
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February 2020 in “Journal of Biomaterials Science Polymer Edition” This study explored the development of GelMet, an electrospun hybrid nanofiber scaffold made from gelatin and PEG methacrylate, which demonstrated strong mechanical properties and effectively supported cell growth in vitro, suggesting its potential for skin tissue engineering applications.
5 citations
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July 2023 in “World Journal of Stem Cells” In a study using a rat model, researchers developed injectable hydrogels from antler reserve mesenchyme which enhanced regenerative healing of full-thickness cutaneous wounds by creating a fetal-like niche that increased stem cell presence and modulated gene expression related to wound healing.
10 citations
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April 2023 in “Acta biomaterialia” This study reported that a newly developed bioadhesive and injectable hydrogel dressing, incorporating hyaluronate-gelatin and the antibiotic doxycycline, accelerated burn wound healing and skin regeneration in rats, highlighting its potential for clinical applications in burn injury therapy.
6 citations
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March 2023 in “Materials” In this study, researchers developed an acellular bioscaffold made from ovine tendon collagen with an antibacterial coating for treating skin wounds. They found that genipin crosslinking improves the scaffold's properties, and with plasma polymerisation, it enhances antibacterial activity, potentially benefiting wound healing.
July 2026 in “Materials Today Bio” This study developed a novel hydrogel that improved healing in diabetic infected wounds on mobile sites by controlling infection, inflammation, and mechanical stress, promoting skin regeneration without excess scarring.
June 2019 in “PRISM (University of Calgary)” This research reported that dermal progenitor cells can enhance split-thickness skin graft outcomes by improving dermal layer qualities and reducing itch and offer potential in skin wound healing using a flowable hydrogel for better cell delivery and survival.
February 2024 in “Advanced Functional Materials” This study reported that a newly developed hydrogel patch, designed to recruit regulatory T cells through ROS-triggered release of CCL22, improved wound healing and hair follicle regeneration in a diabetic mouse model by scavenging ROS, thereby protecting Tregs and suppressing Th17 cells.
75 citations
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January 2011 in “Plastic and Reconstructive Surgery” This review discusses the use of dermal regeneration templates for treating burn injuries and other wounds, highlighting their effectiveness in reducing scars and aiding in regenerative processes, but reports no new clinical results.
May 2022 in “Journal of Immunology” In this study, a TGF-β mimic molecule from Heligmosomoides polygyrus was observed to enhance wound healing in mice, with improved tissue regeneration and specific immune cell recruitment without increased scarring.
June 2026 in “Precision medicine and engineering.” In this study, researchers created a hydrogel that reduces oxidative stress and releases a pro-angiogenic drug in response to enzyme activity, which accelerated healing and improved tissue regeneration in chronic diabetic wounds during in vivo experiments.
This study found that keratin-gelatin composite films effectively promoted early wound healing and full-thickness skin graft acceptance in dogs, outperforming bFGF-gelatin films.
7 citations
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January 2025 in “ACS Applied Materials & Interfaces” This study developed a zinc-infused egg white and GelMA hydrogel that enhanced cellular processes crucial for wound healing, including fibroblast proliferation and collagen expression, and demonstrated promising biocompatibility and bioactivity in vivo, suggesting potential effectiveness in repairing damaged tissues.
17 citations
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August 2024 in “International Journal of Biological Macromolecules” The hydrogel dressings speed up healing and reduce scarring.
6 citations
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July 2021 in “International Wound Journal” In this study, a novel biofilm-dispersing wound gel did not interfere with healing and may enhance it by reducing inflammation in murine models with full-thickness skin wounds.
May 2017 in “Journal of The American Academy of Dermatology” An intact skin barrier is crucial to prevent infection in cases of tether-induced tenosynovitis.
August 2025 in “Biomacromolecules” This study presents a novel composite hydrogel dressing with berberine-loaded silk fibroin microspheres and Calotropis gigantea fibers, demonstrating enhanced antibacterial activity, mechanical strength, and wound healing capabilities in treating chronic and infected wounds.
May 2024 in “Journal of colloid and interface science” This study developed a bilayer bionic skin scaffold that mimics the skin's structure to resist microbial invasion and enhance wound healing, with in vivo animal studies showing improved collagen deposition, neovascularization, and hair follicle formation.
9 citations
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January 2021 in “Acta Cirúrgica Brasileira” This study found that DPG promoted wound healing in rat skin, with increased collagen I density, particularly evident within the first 14 days after injury.
This study observed that mesenchymal stem cell-conditioned medium accelerated burn wound healing in rats by enhancing epidermal growth factor presence, improving wound closure, collagen density, and re-epithelialization compared to the control.
September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study indicates that a helminth-derived protein, TGF-β mimic, may accelerate wound healing and promote regenerative processes in skin tissue by interacting with TGF-β receptors.
January 2025 in “ACS Materials Letters” This study developed a GelMA-based hydrogel system that supports all stages of severe burn wound healing by reducing inflammation and enhancing tissue regeneration, including neovascularization and hair follicle growth, potentially improving clinical outcomes for complex wounds with multidrug-resistant bacterial infections.
1 citations
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March 2023 in “Aggregate” In this study, a hydrogel derived from Andrias davidianus secretion, combined with micronized amnion, promoted skin regeneration and achieved scarless healing in rats, suggesting potential for clinical use.