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      Alopecia Areata: A Review

      research Alopecia areta: a review

      January 2026 in “International Research Journal of Modernization in Engineering Technology and Science”
      This review outlines the existing understanding of alopecia areata, detailing its autoimmune nature, clinical presentation, histology, and management strategies, with corticosteroids highlighted as the most popular treatment option.
      Common Topical Medications

      research Common Topical Medications

      October 2018 in “Springer eBooks”
      The document concludes that various topical medications are effective for skin conditions but often cause skin irritation as a side effect.
      Investigating the Mechanisms Underlying the Pathogenesis of Alopecia Areata

      research INVESTIGATING THE MECHANISMS UNDERLYING THE PATHOGENESIS OF ALOPECIA AREATA

      May 2018 in “White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)”
      In this study, researchers found that alopecia areata patients show a significant reduction in suppressive regulatory T-cells and an increase in inflammatory T-cell populations, suggesting an immunological imbalance contributing to the disease.
      General Dermatology: Comprehensive Overview of Dermatological Conditions

      research General Dermatology

      January 2017 in “Springer eBooks”
      The document explains various skin conditions and their treatments.
      Retinoids

      research Retinoids

      January 2017 in “Clinical approaches and procedures in cosmetic dermatology”
      This research outlines how retinoids, compounds based on vitamin A, activate nuclear receptors to influence cellular processes such as differentiation and carcinogenesis, with benefits like anti-inflammatory properties but requiring careful management of dose-dependent side effects.
      Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice

      research Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice

      1533 citations , October 2008 in “Endocrine reviews”
      This research highlights that engineered mice lacking the vitamin D receptor show multiple health issues similar to human vitamin D deficiency, underscoring the widespread impacts of the vitamin D endocrine system.
      MicroRNA Control of Signal Transduction

      research MicroRNA control of signal transduction

      1066 citations , March 2010 in “Nature Reviews Molecular Cell Biology”
      This review discusses the potential regulation of signal transduction pathways by microRNAs in animal cells, aiming to identify biological processes that may be influenced by miRNA-mediated regulation, but it reports no new experimental outcomes.
      Vitiligo: A Comprehensive Overview

      research Vitiligo: A comprehensive overview

      532 citations , August 2011 in “Journal of the American Academy of Dermatology”
      This article discusses the clinical presentation, histopathologic findings, and pathogenesis hypotheses of vitiligo without reporting new clinical results.
      Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition

      research Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition

      451 citations , March 2005 in “Endocrine Reviews”
      This paper discusses the role of steroid sulfatase in hormone-dependent tumors and highlights the development of potent inhibitors, noting the commencement of a phase I trial for one inhibitor in postmenopausal breast cancer patients.
      Alopecia Areata: An Autoimmune Disease Causing Hair Loss

      research Alopecia Areata

      421 citations , April 2012 in “The New England Journal of Medicine”
      Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
      Obesity and the Skin: Skin Physiology and Skin Manifestations of Obesity

      research Obesity and the skin: Skin physiology and skin manifestations of obesity

      405 citations , May 2007 in “Journal of The American Academy of Dermatology”
      This review discusses the profound impact of obesity on skin physiology and dermatologic conditions and reports no new experimental results, recommending awareness and treatment strategy development for obesity-associated dermatoses.
      Alopecia Areata Update

      research Alopecia areata update

      391 citations , January 2010 in “Journal of The American Academy of Dermatology”
      This article reviews the clinical presentation and histopathologic features of alopecia areata and proposes a hypothesis for its development, but it reports no new clinical results.
      Polycystic Ovary Syndrome: Comprehensive Overview

      research Polycystic Ovary Syndrome

      257 citations , July 2018 in “Obstetrics & Gynecology”
      This review discusses the various phenotypes and diagnostic challenges of polycystic ovary syndrome, highlighting its complex pathophysiology and associated health risks, and reports no new clinical results.
      Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis

      research Transforming growth factor-β in stem cells and tissue homeostasis

      245 citations , January 2018 in “Bone Research”
      This review discusses the role of TGF-β signaling in stem cell recruitment and tissue regeneration, indicating that abnormalities in TGF-β activation contribute to various major diseases and suggesting avenues for therapeutic intervention.
      Acne

      research Acne

      231 citations , April 2005 in “The New England Journal of Medicine”
      This article discusses the treatment considerations for a 17-year-old boy with a six-month history of acne but reports no new research findings.
      Cutaneous Adverse Effects of Targeted Therapies

      research Cutaneous adverse effects of targeted therapies

      192 citations , January 2015 in “Journal of the American Academy of Dermatology”
      This review discusses skin-related toxicities associated with targeted cancer therapies and emphasizes the need for dermatologists to understand and manage these adverse effects, but reports no new experimental results.
      Alopecia Areata: A Review of Disease Pathogenesis

      research Alopecia areata: a review of disease pathogenesis

      191 citations , May 2018 in “British journal of dermatology/British journal of dermatology, Supplement”
      This study reviewed recent theories on alopecia areata's pathogenesis, highlighting its autoimmune nature due to immune privilege disruption in hair follicles, and noted current treatments have limited efficacy with high relapse rates, underscoring the need for further research into its mechanisms for better therapies.