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The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Testosterone therapy increases bone density in older men with low testosterone levels.

Targeting colon cancer stem cells might lead to better treatment results.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

The document likely offers guidance on treating a woman's excessive hair growth, considering her symptoms and obesity.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Tofacitinib is effective and safe for severe hair loss, but full regrowth is less likely after 10 years of hair loss.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

Knowing about finasteride's sexual side effects increases reported dysfunction.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.