December 2006 in “Cancer Epidemiology and Prevention Biomarkers” This review highlights the low uptake of tamoxifen and finasteride for cancer chemoprevention in primary care, citing various barriers and indicating a need for safer, more affordable options.
This study suggests that the long non-coding RNA Xist is a key factor in sex differences in systemic lupus erythematosus and rheumatoid arthritis, affecting immune cell behavior and inflammatory pathways in women.
45 citations
,
July 2009 in “Journal of human genetics” This study found that an SNP in the FGFR2 gene, rs4752566, was significantly associated with hair thickness in Asian populations, suggesting an effect on hair morphology through altered FGFR2 expression levels.
27 citations
,
January 2010 in “Animal” In these studies, researchers found that Peruvian camelids reach mature skin follicle development early, with specific cuticular characteristics useful for distinguishing fleece types, while Bolivian llamas have a mature follicle apparatus present at birth.
19 citations
,
June 1999 in “Steroids” This study found that compound 10 inhibited testosterone conversion to DHT in hamster flank organs and seminal vesicles, whereas compound 11's inhibitory effect varied with dose, linked to halogen electronegativity differences.
9 citations
,
March 2013 in “ISRN Stem Cells (Online)” This study demonstrated that human dermal mesenchymal stem cells can be differentiated into cardiomyocytes using 5-azacytidine, suggesting potential future applications for treating myocardial infarction.
May 2023 in “Frontiers in Endocrinology” This study found that tildacerfont treatment in males with congenital adrenal hyperplasia reduced androgen levels and improved markers of testicular function, suggesting potential benefits for male reproductive health.
This dissertation reported that the loss of Ovol2 impairs hair follicle regeneration and wound repair in mice, highlighting its role in regulating directional migration of epithelial cells.
4 citations
,
March 2006 in “Journal of renal nutrition” This study found that hemodialysis patients taking water-soluble vitamins had a 16% lower mortality risk compared to those not taking any, but the specific supplementation needed remains unclear.
2 citations
,
August 1987 in “Australasian Journal of Dermatology” This review discusses skin diseases related to contraceptive use, reporting potential issues with oral contraceptives and infrequent reactions to mechanical or barrier methods without new clinical findings.
In this study, six types of cold-pressed oils commonly found in the Polish market were analyzed for their health-promoting compounds and antioxidant activity, revealing them as valuable sources of bioactive compounds like polyunsaturated fatty acids, tocopherols, sterols, and polyphenols, without exceeding recommended deterioration parameters.
January 2012 in “TRANSACTIONS OF THE JAPAN SOCIETY FOR AERONAUTICAL AND SPACE SCIENCES AEROSPACE TECHNOLOGY JAPAN” This paper outlines the research plan and current progress of a study analyzing mineral metabolism changes in astronauts by examining hair shafts after long-term space flight, with no new results yet.
1 citations
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January 2023 in “eCite Digital Repository (University of Tasmania)” This study suggests that the differences in aluminium tolerance between ET8 and ES8 wheat cultivars are linked to a complex suite of physiological mechanisms, including variations in malate and K+ release, Ca2+ homeostasis, and SV channel properties, rather than solely malate efflux.
249 citations
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November 2003 in “Clinical endocrinology” This review discusses the complex etiology of polycystic ovary syndrome (PCOS), highlighting its association with insulin resistance and hyperandrogenism, but reports no clinical findings; the authors suggest further investigation of the pathophysiological mechanisms.
82 citations
,
September 2020 in “Briefings in Bioinformatics” This study identified shared genes and pathways in idiopathic pulmonary fibrosis patients with COVID-19, suggesting these may increase mortality and pointing to potential drug targets for treatment.
75 citations
,
November 2016 in “Medicines” This review discusses the properties and therapeutic potentials of beta-sitosterol, highlighting a need for more detailed studies on its mechanisms and long-term effects in humans; it reports no new results.
27 citations
,
March 2017 in “Current Clinical Pharmacology” In this review, the authors discuss the pharmacology of dutasteride and compare its efficacy to finasteride for treating androgenetic alopecia, highlighting dutasteride's effectiveness demonstrated in several clinical trials.
24 citations
,
April 2007 in “European Journal of Pharmaceutics and Biopharmaceutics” This study found that artocarpin delivered via alginate/chitosan microparticles effectively suppressed the growth of hamster flank organs compared to artocarpin in solution form, without significant systemic effects.
23 citations
,
January 2022 in “Biomaterials Science” Non-viral vectors show promise for safe and effective CRISPR/Cas9 gene editing in treating diseases.
17 citations
,
February 2023 in “Cosmetics” This study explores the use of bioinspired 3D printed hollow microneedles, which may offer improved delivery of anti-wrinkle formulations, and reviews the current landscape and challenges of existing wrinkle treatments and microneedle technology.
14 citations
,
May 2008 in “Journal of proteome research” This study found that dutasteride reduced β-amyloid plaque load in a cerebral amyloidosis model, seemingly linked to mitochondrial apoptosis and autophagy processes.
12 citations
,
August 2004 in “Veterinary Dermatology” This study found that treating cats infested with Lynxacarus radovskyi using Fipronil resulted in complete resolution of the infestation by day 15.
11 citations
,
January 2015 in “Journal of nanomedicine & biotherapeutic discovery” This review discusses the applications of nanotechnology in dermatology and cosmetics, describing types of nanoparticles, their potential uses, and considerations regarding their safety, but it presents no new clinical results.
9 citations
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January 2019 in “International Journal of Trichology” In this study, combining topical calcipotriol with mometasone results in greater improvement in alopecia areata treatment compared to using mometasone alone, as evidenced by a more significant reduction in SALT score over 24 weeks.
9 citations
,
August 2013 in “Middle East Fertility Society Journal” This study found that the hospital-based prevalence of polycystic ovarian syndrome among Omani women of reproductive age was 2.8%, similar to rates reported in other countries.
7 citations
,
November 2003 in “Current Opinion in Obstetrics & Gynecology” This review summarizes recent studies on metformin for polycystic ovary syndrome, reporting its beneficial effects on endocrine, metabolic, and reproductive outcomes, but highlights ongoing debate about its mechanisms.
6 citations
,
May 2022 in “Frontiers in Medicine” This study observed that COVID-19-related stress and fear were potentially associated with an increased occurrence of hair diseases like telogen effluvium, alopecia areata, and seborrheic dermatitis among medical students in Bangladesh.
5 citations
,
May 2020 in “Clinical Phytoscience” In this study, methanol extract of Cuscuta reflexa leaves significantly reduced blood glucose and improved insulin and liver function in alloxan-induced diabetic rats, indicating potential as an antidiabetic and organ-protective agent.
5 citations
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January 2018 in “Acta Dermatovenerologica Alpina Pannonica et Adriatica” This case study highlights congenital atrichia with papular lesions as a cause of total body hair loss, characterized by the absence of hair follicles and the presence of skin-colored papules.
4 citations
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December 2020 in “Journal of the American Academy of Dermatology” Pulling 2 or fewer hairs is normal for all hair types, including Afro- and Asian-textured hair.