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Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Hormones are crucial for regulating body functions and imbalances can lead to health issues.

Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by blocking male sex hormones.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

Diphenyl cresyl phosphate has low toxicity but can harm the liver, kidneys, adrenal glands, and testicles at high doses.

Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by affecting androgen functions and suppressing certain hormones.

New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.

Acne severity in women may not be linked to increased male hormone indicators like excess body hair, menstrual irregularities, or hair loss.

Different hair growth phases affect how follicles respond to X-rays, and hormones like testosterone and dihydrotestosterone play a key role in baldness; transplanted hair can grow on bald scalp areas.

Melatonin affects mouse skin and may regulate skin functions.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

Male hormones control a specific gene in hamster skin, with different hormones having varying effects.

Radiation damages salivary glands by harming blood vessels, but antioxidants might help protect them.

IL-17C is important in inflammatory skin diseases and could be a target for treatment.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Hidradenitis suppurativa improves with antiandrogen therapy.

Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Cutaneous lupus patients have higher levels of certain immune cells in their blood and skin.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.