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Eating a high-glycemic diet may worsen acne by increasing certain protein levels and expressions in the skin.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

SkQ1 antioxidant improved health and lifespan in mice.

Acne patients have higher levels of mTOR in their skin, which could be linked to future metabolic disease.

Coal tar shampoo increases enzyme activity in hair follicles, enhancing carcinogen binding to DNA.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

The best way to treat acne is to prevent healthy skin glands from turning into acne lesions by controlling the triggers early on.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

Smaller particles of the drug carrier penetrated skin better, with 300 nm size being best for targeting hair follicles.

A new method can quickly and accurately detect drugs in hair.

Iontophoresis improves minoxidil delivery for alopecia treatment.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

A protein complex called mTORC1 likely affects when hair growth starts in mice.

Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.

Nanoparticles can effectively deliver spironolactone to hair follicles for treating alopecia and acne.

Calcipotriol scalp solution works better than coal tar shampoo for treating scalp psoriasis and is safe for long-term use.

The study found that analyzing certain cell signaling pathways is not a reliable method to tell apart two types of skin tumors.

Genomic approach finds new possible treatments for hair loss.

Curcumin may help reverse aging by targeting specific genes.

New treatments for non-small cell lung cancer are being tested, with some already in use, focusing on immune response and targeting cancer cells, but side effects vary.

Adding a second method to PROTACs could improve cancer treatment.

New targeted cancer drugs can cause skin side effects, and managing them requires patient education and timely care.

Niosomes are the most effective at delivering drugs to the skin with minimal absorption into the body.

Deleting the p63 gene in certain cells causes problems in thymus development and severe hair loss in mice.

Nanoparticle-based drug delivery to hair follicles is more effective when tested under conditions that match skin behavior.

The mTOR pathway may be involved in the development of hair follicle tumors, with higher activity in malignant tumors.

Five molecular elements identified as potential future targets for hair loss therapy.

A woman with acne and baldness was found to have a rare ovarian condition but successfully had a child through fertility treatment.