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Integrin β1 is crucial for liver structure and function, preventing fibrosis.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

NIPP1 is important for healthy skin and could help treat skin inflammation.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

B2m-free HLA variants may be a new class of HLA important in immune responses and diseases.

Hormones and stretching both needed for nipple area skin growth in mice.

Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.

High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

CRISPR/Cas9 has improved precision and control but still faces clinical challenges.

Hoxc13 gene affects wool length in Gansu alpine fine-wool sheep.

Sensory neuron changes and Merkel-cell changes in the skin happen independently during normal skin maintenance.

Sensory neuron remodeling and Merkel-cell changes in the skin happen independently.

Sensory neuron remodeling and Merkel-cell changes happen independently during skin maintenance.

Sensory neuron and Merkel-cell changes in the skin happen independently during normal skin maintenance.

Sensory neuron and Merkel cell changes in the skin happen independently during normal skin maintenance.

Sensory neurons and Merkel cells remodel at different rates during normal skin maintenance.

Sensory neuron and Merkel cell changes in the skin happen independently during normal skin maintenance.

Skin grafting and wound treatment have improved, but we need more research to better understand wound healing and create more effective treatments.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.

c-Myc activation in mouse skin increases sebaceous gland growth and affects hair follicle development.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.

Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.

Overexpressing follistatin in mice delays wound healing and reduces scar size.

Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.

Mice without the vitamin D receptor are more prone to UV-induced skin tumors.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.