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Tofacitinib is effective and safe for severe hair loss, but full regrowth is less likely after 10 years of hair loss.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Low iron levels may be linked to some types of hair loss in women.

Alopecia areata is a common autoimmune disease affecting about 2% of people, causing significant disability and often associated with mental health issues and other autoimmune conditions.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.

Probiotic bacteria improved skin and hair health in aged mice.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Cepharanthine, a Japanese hair loss drug, shows promise as a COVID-19 treatment but needs more testing.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Both ruxolitinib and tofacitinib are effective and safe for treating severe alopecia areata, but relapses are common.

Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.

Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.

Topical immunotherapy, especially with DPCP, is effective for treating severe alopecia areata.

The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Apremilast was not effective in treating moderate-to-severe alopecia areata.

Tofacitinib citrate improved nail dystrophy and pain in patients with alopecia universalis without causing side effects.

Antimicrobial lotion reduces inflammation and increases hair density in hair loss patients.

Pseudopelade of Brocq is a unique hair loss condition, but its cause and development are still not fully understood.

Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.

ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.