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New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

Light therapy might help treat hereditary hair loss by improving hair follicle growth in lab cultures.

Liposomes show promise for delivering CRISPR for gene editing but face challenges like delivery efficiency and safety concerns.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.

17β-estradiol can reduce inflammation in the skin.

The nail matrix has a reduced immune response, protecting it from autoimmunity.

People with atopic dermatitis have different skin bacteria, and targeting these bacteria might help treat the condition.

Non-coding RNAs are crucial for skin development and health.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.

Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.

Different PIN proteins affect plant root hair growth by changing how auxin is transported.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Chicken feather gene mutation helps understand human hair disorders.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.

The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Long-term fluticasone treatment does not harm the immune system in horses with heaves.

Superficial cryotherapy significantly improves eyebrow hair growth in alopecia universalis patients.

Frontal fibrosing alopecia is a scarring hair loss condition mainly affecting older women, with no known cause and treatments that may help stabilize hair loss.

Some people with primary cicatricial alopecia also have inflammatory bowel disease, suggesting a possible connection.

Lack of Cisd2 disrupts calcium balance in cells, leading to poorly functioning neutrophils.

Innovative methods are reducing animal testing and improving biomedical research.

Non-classic congenital adrenal hyperplasia (NCCAH) can mimic PCOS and requires genetic testing for proper diagnosis and treatment.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.