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T-cell reconstitution after thymus transplantation can cause hair whitening and loss.

New treatments targeting T-cell pathways are needed for better alopecia areata management.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.

CD80CD86 deficiency causes hair loss by disrupting regulatory T cells.

Tofacitinib improved ulcerative colitis, skin ulcers, and hair loss in a patient who didn't respond well to other treatments.

Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.

Certain immune cells contribute to severe hair loss in chronic alopecia areata, with Th17 cells possibly having a bigger impact than cytotoxic T cells.

Dandruff is linked to increased T cells and weakened immune protection in hair follicles.

Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Hair loss in mice starts with immune cells damaging hair roots before it becomes visible.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Cyclosporin effectively and safely treated skin diseases in three pets with no side effects.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Herpes gestationis is linked to certain antigens, atopic eczema affects T cell populations and may be eased by breastfeeding, higher doses of anti-androgen treatment can improve androgenic alopecia, topical minoxidil increases hair thickness, long-term methotrexate therapy can cause liver fibrosis in psoriasis patients, and Lichen Sclerosus et Atrophicus patients aren't at higher risk for autoimmune disorders.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Activin increases skin tumor formation, skin Tregs help hair growth, lymph-node removal doesn't improve melanoma survival, cells can revert to stem cells in wound healing, and skin bacteria produce peptides that may treat infections.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

Cyclosporine A can reduce inflammation in dogs with sebaceous adenitis, but ongoing treatment is needed.

External factors can cause skin cancer cells that usually don't spread to grow and form tumors in mice.

Umbilical cord cells safely improve healing in long-term nonhealing wounds better than a placebo.

A woman with lupus had blood cell destruction, treated successfully with medication.

Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.

The conditions alopecia areata, primary sclerosing cholangitis, and ulcerative colitis may be linked by shared autoimmune and cell death mechanisms.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

People with vitiligo may have a higher rate of Helicobacter pylori infection, but the infection's severity doesn't affect how severe the vitiligo is.

Ruxolitinib may help treat hair loss by reducing inflammation, promoting hair growth signals, and protecting hair follicle immunity.