research IL-33 Contributes to the Pathological Changes of Hair Follicles in Psoriasis: A Potential Target for Psoriatic Alopecia
IL-33 is linked to hair follicle damage in psoriasis and could be a treatment target for hair loss in this condition.
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research Discovery of Autoantigens in the Hair Loss Disorder Alopecia Areata: Implications of Posttranslational Modifications
Scientists are still unsure what triggers the immune system to attack hair follicles in Alopecia areata.
research Tyrosine Kinase 2 Inhibition Ameliorates the Phenotype of Lesional Alopecia Areata Scalp Skin Ex Vivo, and Reverses the Induction of Human Alopecia Areata in a Humanized Mouse Model
TYK2 inhibition may help treat alopecia areata by promoting hair growth and reducing immune response.
research CAQ Corner: Basic Concepts of Transplant Immunology
The document explains how the immune system reacts to organ transplants and the treatments used to prevent rejection.
research Role of FOXN1 in Xenopus Laevis Thymopoiesis
FOXN1 is crucial for thymus development and immune response in Xenopus laevis.
research Fibrosing Alopecia in a Pattern Distribution
Fibrosing alopecia in a pattern distribution is a new type of scarring hair loss that resembles common baldness and an autoimmune skin disease.
research A Rare Case of Complete Vogt-Koyanagi-Harada Disease Presenting to a Tertiary Care Hospital in Late Stage: Clinical Features, Diagnosis, and Management
A young woman with late-stage Vogt-Koyanagi-Harada disease was successfully treated at a hospital.
research Alymphoid Cystic Thymic Dysgenesis - FOXN1 Gene Mutation: A Rare Case Report of Two Siblings
Two siblings had a rare immune disorder caused by a FOXN1 gene mutation.
research Evaluation of Serum Apelin-13 in Psoriasis Vulgaris Patients
People with psoriasis have higher levels of Apelin-13 in their blood than healthy people.
research Roles of the Hedgehog Signaling Pathway in Cutaneous Physiology and Oncology
The Hedgehog Signaling Pathway is important for skin and hair development and skin cancer treatment, but more research is needed to understand it fully.
research LFA-1 Blockade Prevents the Onset of Alopecia Areata in C3H/HeJ Mice
Blocking LFA-1 prevents hair loss in mice.
research British Hair and Nail Society
Hair regrowth was seen in 83% of children with alopecia, immune system plays a role in the condition, and various treatments showed effectiveness for hair and nail disorders.
research Computer-Assisted Epitope Prediction Revealed Potential Autoantigens Associated with Human Alopecia Areata
Melanogenesis-related proteins may trigger immune responses in alopecia areata patients.
research Patients with Compound Heterozygous Mutations in Forkhead Box N1 Have Severe Immunodeficiency While Maintaining Normal Skin and Hair Development
Patients with certain FoxN1 gene mutations have severe immune issues but normal skin and hair.
research Small Molecule Wnt Pathway Inhibitor (SM04755) as a Potential Topical Psoriasis Treatment
SM04755 may be an effective topical treatment for psoriasis.
research Predictive Modeling of Drug Response and Mechanism of Action in Alopecia Areata Clinical Trials
Researchers found three different ways drugs work to treat hair loss from alopecia areata and identified key factors for personalized treatment.
research Identification of Differentially Expressed miRNAs in Alopecia Areata That Target Immune-Regulatory Pathways
Researchers found that certain miRNAs, which affect immune system regulation, are differently expressed in mice with a hair loss condition compared to healthy mice.
research General Dermatology: Comprehensive Overview of Dermatological Conditions
The document explains various skin conditions and their treatments.
research Ectrodactyly, Ectodermal Dysplasia, and Cleft Lip/Palate Syndrome with Concomitant Lymphopenia: A Novel TP63 Mutation
A new TP63 mutation was found in a baby with EEC syndrome, showing the need for TREC testing to check for immune issues.
research Psoriasis and Hepatitis C: Improvement with Interferon
A woman's psoriasis improved after hepatitis C treatment with interferon, despite interferon's risk of worsening skin conditions.
research Results of Stage I in a Phase II Randomized Bilateral Comparison of Bexarotene 1% Topical Gel in Alopecia Areata
Bexarotene 1% topical gel helped some patients with alopecia areata regrow hair.
research Adipose Tissue Remodeling via TSLP-Mediated IL-4/IL-13 Signaling: Implications for Atopic Dermatitis and Skin Barrier
TSLP affects atopic dermatitis by increasing sebum and reducing fat through IL-4/IL-13 signaling.
research Microarray Gene Expression Analysis of Lesional Skin in Canine Pemphigus Foliaceus
Canine pemphigus foliaceus involves significant immune activity and shares similarities with human pemphigus.
research Clinical and Immunological Impact of Booster Immunization With Recombinant mRNA Vaccines for SARS-CoV-2 in Patients With Pemphigus and Bullous Pemphigoid
Booster shots of mRNA vaccines for COVID-19 increased protective antibodies without worsening autoimmune skin conditions in patients.
research Overview of the Role of 308 Monochromatic Excimer Phototherapy for the Treatment of Alopecia Areata
308 excimer phototherapy is a safe and effective way to treat hair loss from Alopecia Areata.
research IL-15 Prolongs Hair Growth and Acts as a Guardian of Human Hair Follicle Immune Privilege
IL-15 helps maintain hair growth and protects the immune status of hair follicles.
research Greasy Hair Against Obesity: TSLP-Induced Sebum Production Reduces Fat
Increasing sebum production might help reduce fat and improve metabolism.
research Updates in the Pathogenesis of Alopecia Areata
Alopecia areata is an autoimmune condition causing hair loss, linked to genetic factors and immune system issues, with no cure yet.
research Combination of Topical Anthralin and Calcipotriene in Alopecia Areata: A Discussion of the Mechanisms of Action
Using anthralin and calcipotriene together might help treat tough cases of alopecia areata, but more research is needed to understand how it works.
research Promotion of Hair Growth in Alopecia Areata by Topical Treatment of HDAC Inhibitors
HDAC inhibitors, like Vorinostat and Entinostat, can help regrow hair in alopecia areata.