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PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

The document tests knowledge and decision-making in hematology through multiple-choice questions.

The document provides 70 multiple choice questions to improve haematology skills.

Chronic kidney disease can cause hair loss, which may be related to zinc deficiency or certain medications, and sometimes hair grows back when the underlying issue is treated.

Eating a balanced diet with the right vitamins and minerals is important for healthy hair, but too many supplements can be harmful.

Mast cells play a significant role in hair loss conditions like male pattern hair loss and alopecia areata.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Demodicosis is common and often missed, needing more recognition and treatment in skin care.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

The yeast Pityrosporum ovale can cause skin allergies and infections, and antifungal treatments like ketoconazole are effective against it.

Biotin treatment can significantly improve hair loss and motor functions in certain metabolic disorders.

Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.

Stress and emotional factors can worsen skin conditions by affecting the immune system.

Finasteride can cause one-sided breast enlargement, which disappears after stopping the drug.

Female donor to male recipient sex mismatch and positive ACA-IgG are key risk factors for vitiligo and alopecia areata in chronic GvHD patients.

Stump-tailed macaque best for researching hair loss causes and treatments.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

Hair and nails are similar keratin structures with different shapes and growth, affected by the same diseases and environmental factors.

Tamoxifen can cause total hair loss but its benefits outweigh this side effect.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

XEDAR triggers a specific signaling pathway in cells.

A woman's total hair loss was linked to a Borrelia infection and was reversed with appropriate treatment.

Rapamycin may help treat Leigh syndrome by targeting protein kinase C.

Iron deficiency might contribute to hair loss in women.

Young HS patients often have other physical and mental health issues, and research on HS covers a wide range of topics including genetics, triggers, treatments, and the need for more data.

The document says that there are treatments for hair and nail diseases.

The conclusion is that maintaining blinding in clinical trials is crucial for reliable results.