7 citations,
August 2022 in “Journal of Nanobiotechnology” Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.
3 citations,
April 2022 in “International Journal of Molecular Sciences” Scientists turned mouse skin cells into hair-inducing cells using chemicals, which could help treat hair loss.
August 2023 in “Military Medical Research” Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
August 2024 in “Stem Cell Research & Therapy” New regenerative therapies show promise for treating hair loss.
31 citations,
September 2012 in “Journal of biological chemistry/The Journal of biological chemistry” The right amount of retinoic acid is essential for normal hair growth and development.
6 citations,
May 2009 in “Cell transplantation” Green tea component EGCG helps keep rat skin grafts viable longer.
212 citations,
September 2015 in “Journal of Investigative Dermatology” The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.
51 citations,
May 2019 in “Biomaterials” Researchers developed a method to grow hair follicles using special beads that could help with hair loss treatment.
66 citations,
May 2012 in “Scientific Reports” Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.
2 citations,
June 2012 in “Journal of Dermatological Science” The gene HDC is important for the development of hair follicles in newborn mice.
179 citations,
April 2012 in “Nature Communications” Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.
45 citations,
November 2017 in “Biomaterials” Researchers found a new way to create hair-growing structures in the lab that can grow hair when put into mice.
40 citations,
October 2002 in “Endocrinology” Vitamin D3 analogs can promote hair growth in mice genetically prone to hair loss.
121 citations,
May 2009 in “Journal of Ethnopharmacology” Eclipta alba extract may help hair grow similarly to Minoxidil.
101 citations,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.
96 citations,
April 2007 in “Journal of Investigative Dermatology” Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.
72 citations,
January 2001 in “Drugs” Minoxidil and finasteride treat hair loss; more research needed for other options.
51 citations,
May 2013 in “The Journal of Steroid Biochemistry and Molecular Biology” Certain drugs that block specific enzymes can help treat prostate diseases.
47 citations,
May 2012 in “Wiley Interdisciplinary Reviews-Developmental Biology” The conclusion is that understanding how feathers and hairs pattern can help in developing hair regeneration treatments.
19 citations,
November 2001 in “Journal of Investigative Dermatology Symposium Proceedings” Human hair follicles can regenerate and recover after severe injury by going through a brief abnormal resting phase before growing again.
17 citations,
October 2015 in “Medicine and Pharmacy Reports” Animal models are crucial for learning about hair loss and finding treatments.
January 1998 in “Lasers in Surgery and Medicine” Lasers are effective and safe for various medical treatments, including cancer, wound healing, and skin conditions.
93 citations,
February 2009 in “Annals of the New York Academy of Sciences” 5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.
84 citations,
June 2013 in “Stem Cells Translational Medicine” New methods for skin and nerve regeneration can improve healing and feeling after burns.
53 citations,
November 2006 in “Journal of Endocrinology” Prolactin slows down hair growth in mice.
33 citations,
April 2012 in “British Journal of Dermatology” Damaged hair follicle stem cells can cause permanent hair loss, but understanding their role could lead to new treatments.
29 citations,
December 2019 in “Stem Cells Translational Medicine” Fully regenerating human hair follicles not yet achieved.
24 citations,
August 2011 in “Experimental Dermatology” The flap assay grows the most natural hair but takes the longest, the chamber assay is hard work but gives dense, normal hair, and the patch assay is quick but creates poorly oriented hair with some issues.
23 citations,
February 2020 in “PLOS genetics” Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.
23 citations,
October 2006 in “Journal of Investigative Dermatology” Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.