33 citations
,
December 2012 in “NMR in Biomedicine” This study reports that microencapsulation of therapeutic cells with contrast agents enables visualization across multiple imaging modalities, potentially improving cellular immunoprotection and tracking after transplantation.
January 2015 in “D-Scholarship@Pitt (University of Pittsburgh)” This dissertation investigated barriers to clinical translation of adipose-derived mesenchymal stem cell-based vascular grafts, highlighting issues with thrombosis in diabetic patients and proposing alternative cell sources to improve applicability.
223 citations
,
December 2010 in “The Journal of Sexual Medicine” This review discusses persistent adverse effects of 5α‐reductase inhibitors, like diminished libido and erectile dysfunction, in some patients and highlights the need for patient discussions before therapy, especially for androgenetic alopecia.
87 citations
,
July 2009 in “Journal of Cell Science” The researchers found that corneodesmosin is crucial for maintaining skin barrier integrity and hair follicle architecture in mice, with its deletion leading to severe skin and hair abnormalities.
74 citations
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June 2018 in “Cell death and disease” In this study, researchers found that depleting mtDNA in mice caused skin wrinkles and hair loss but restoring mitochondrial function reversed these effects, highlighting mtDNA's significant role in skin and hair health.
7 citations
,
March 2018 in “Journal of The American Academy of Dermatology” This study found that pediatric HSCT recipients, especially those with chronic graft-versus-host disease, are at risk for developing various nonmalignant late cutaneous changes such as vitiligo, psoriasis, alopecia, and nail changes.
3 citations
,
June 2025 in “Stem Cell Research & Therapy” Hair follicle-derived melanocyte transplant could effectively treat vitiligo by restoring skin color.
13 citations
,
October 2017 in “Biomedicine & Pharmacotherapy” In this study, ethyl acetate fraction of Eclipta alba was found to inhibit adipogenesis and reduce dyslipidemia in hamsters, suggesting potential as an herbal treatment for obesity.
1 citations
,
April 2025 in “Pigment Cell & Melanoma Research” This article reviews the underlying mechanisms of segmental vitiligo with white hair, focusing on skin and hair follicle melanocytes, and proposes potential targets for treatment, highlighting neuroendocrine factors as possible contributors to the condition.
April 2017 in “Journal of Investigative Dermatology” This study found that long-term hair follicle stem cells originate from embryonic progenitor cells in a niche with reduced Wnt/β-catenin signaling, which is essential for their specification.
64 citations
,
August 2013 in “Mayo Clinic Proceedings” This review discusses current concepts in wound repair and suggests that these evolving paradigms might also explain regenerative processes in various organ systems, but it reports no new research findings.
30 citations
,
March 2017 in “ACS biomaterials science & engineering” This review discusses the structure and regenerative potential of hair follicles, highlighting their role in wound healing, stem cell populations, and keratin-based biomaterials, but it reports no new clinical results.
May 2026 in “Science Advances” This research observed that translation initiation shifts from cap-dependent to IRES-mediated pathways varied across tissues and cell types under stress and differentiation conditions in mice, with low IRES/Cap ratios signaling high stemness and potential multipotency, mediated by the RNA processing protein PTBP1.
January 2026 in “Frontiers in Cell and Developmental Biology” This review discusses the molecular mechanisms and clinical applications of autologous platelet-derived products for TMJ regeneration, but reports no new clinical results.
January 2023 in “Sibirskij medicinskij vestnik” This analysis explores possible causes of menstrual irregularities in women with PCOS following COVID-19, but reports no new clinical findings.
56 citations
,
October 2007 in “Journal of Biological Chemistry” This study concluded that dilated cardiomyopathy in Ctsl-deficient mice is mainly due to the lack of cathepsin L in cardiomyocytes, with additional heart stress from the fur defect.
146 citations
,
July 2018 in “Regenerative Medicine” This review updates the understanding of fibroblast heterogeneity in wound healing, discussing advancements in fibroblast roles and potential therapies, but it reports no new clinical results.
54 citations
,
October 2022 in “Cells” This review discusses the therapeutic potential of mesenchymal stem cell-derived extracellular vesicles and modern technologies like 3D bioprinting but reports no new clinical results.
26 citations
,
August 2016 in “Translational Andrology and Urology” This review discusses the impact of medical and surgical treatments for LUTS/BPH on ejaculatory function, highlighting that most treatments negatively affect it, except for some minimally invasive surgical therapies and specific medical therapies.
11 citations
,
August 2014 in “Current Urology Reports” This review discusses the known effects of medications for benign prostatic hyperplasia on sexual function and mechanisms of dysfunction but reports no new clinical results.
February 2026 in “The Journal of Sexual Medicine” In this case report, goserelin, a GnRH agonist, was effective in managing stuttering priapism and improving erectile function in a patient with sickle cell disease, suggesting potential for last-line treatment.
April 2021 in “Journal of Investigative Dermatology” This study found that CD1a-restricted CD4+ T cells responsive to lysyl-phosphatidylglycerol were more frequent in the blood of atopic dermatitis patients, suggesting a potential role in the disease's Th2-mediated pathology.
57 citations
,
July 2009 in “Urology” This study found that finasteride may decrease and control the frequency of priapism episodes in patients with sickle cell anemia, with fewer side effects compared to other treatments.
2 citations
,
September 2016 in “Journal of skin and stem cell” This study observed that acne was strongly associated with higher BMI, alopecia, menstrual dysfunction, positive familial history, and overuse of sweet and fatty foods among dermatology patients.
40 citations
,
April 2014 in “Genes & Development” The researchers reported that in mice, prolactin signaling in the skin epithelium inhibits hair follicle stem cell activation, promoting quiescence during periods of high serum prolactin like pregnancy and lactation.
September 2023 in “Medical and Clinical Case Reports” This source explores the association between alopecia areata and thyroid dysfunction, highlighting a particularly strong link with Hashimoto thyroiditis and hypothyroidism.
9 citations
,
January 2017 in “Elsevier eBooks” This chapter discusses the skin stem cell niche as a complex ecosystem and highlights the diverse components and interactions that influence stem cell function, but it reports no new experimental results.
129 citations
,
January 2007 in “Otology & Neurotology” This study found that delivering math1 via an adenovector led to vestibular hair cell regeneration and improved balance function in ototoxin-treated adult mice.
July 2021 in “International Ophthalmology” Female hair loss patients more likely to have dry eye and gland issues.
November 2025 in “Frontiers in Immunology” This study introduces stem cell activity as a key factor influencing the effects of IFN-γ and TGF-β1 on autoimmune disease dynamics, showing that varying cytokine levels can modulate stem cell activity and immune privilege, impacting tissue regeneration and disease flares.