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Alopecia areata can be reversed by JAK inhibitors, promoting hair regrowth.

Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Memory regulatory T cells need IL-7, not IL-2, to stay in peripheral tissues.

Cytotoxic T cells cause hair loss in chronic alopecia areata.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.

Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.

Certain immune cells contribute to skin autoimmune diseases, and some treatments can reverse hair loss in these conditions.

Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.

Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.

The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.

Regulatory T cells are essential for normal and improved wound healing in mice.

VDC-1101 shows potential as a treatment for canine cutaneous T-cell lymphoma.

Human dermal γδT-cells respond to stress in hair follicles, contributing to hair loss.

ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.

Treg dysfunction is linked to various autoimmune skin diseases, and understanding Treg properties is key for new treatments.

Targeting Vδ1+T-cells may help treat alopecia areata.

People with alopecia areata have fewer regulatory T-cells than those with other skin conditions.

Certain immune cells contribute to severe hair loss in chronic alopecia areata, with Th17 cells possibly having a bigger impact than cytotoxic T cells.

Some patients with a type of skin lymphoma can experience a rare, non-scarring hair loss that looks like another hair loss condition but has distinct features.

Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.

SV40 T antigen in hair follicles causes abnormal hair and health issues in mice.

Gamma delta T cells in the skin help with healing and defense but can also cause autoimmune issues, and more research is needed to understand how they are activated.

Antroquinonol may help prevent skin depigmentation by suppressing certain immune cells.

The document concludes that DAB389-IL2 is promising for treating refractory cutaneous T-cell lymphoma, but more research is needed on its effectiveness and side effect management.

The growth of the Epstein-Barr virus in the patient's cells was linked to the worsening of her lymphoma.

NKG2D+CD4+ T cells are higher in alopecia areata patients and may be involved in the disease.