research Persistent Virilization and Vasomotor Symptoms in a Transman 5 Years Post Testosterone Withdrawal
A transman experienced lasting virilization symptoms after stopping testosterone, which were resolved with estradiol treatment.
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540-570 / 840 results research Effects of Camellia Oleifera Seed Shell Polyphenols and 1,3,6-Tri-O-Galloylglucose on Androgenic Alopecia via Inhibiting 5α-Reductase and Regulating Wnt/β-Catenin Pathway
Camellia oleifera seed shell polyphenols and 1,3,6-tri-O-galloylglucose can help treat hair loss by reducing certain hormones and promoting hair growth.
research Androgen Biosynthetic Pathways in the Human Prostate
DHT in the human prostate is produced through multiple pathways, not just from testosterone.
research Androgens and Ovarian Function: Translation from Basic Discovery Research to Clinical Impact
Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
research Serum Vitamin D, Ferritin, and TSH in Patients with Telogen Effluvium: A Retrospective Epidemiological Study
Many patients with hair loss had low iron and vitamin D levels, but thyroid issues were not common.
research Female Pattern Alopecia: Its Importance in Medicine and Aesthetic Surgery
Female pattern hair loss is common and should be treated early to prevent worsening, with Minoxidil being the main approved treatment.
research Human Type 3 5α-Reductase Is Expressed in Peripheral Tissues at Higher Levels Than Types 1 and 2 and Its Activity Is Potently Inhibited by Finasteride and Dutasteride
Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.
research An Attempt to Assess the Magnitude of Endogenous Androgen Production in a Case of the Adrenogenital Syndrome
A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.
research Autophagy Is Essential for Maintaining the Growth of a Human Mini-Organ: Evidence from Scalp Hair Follicle Organ Culture
Autophagy is important for human hair growth and health.
research Potential Targets in the Discovery of New Hair Growth Promoters for Androgenic Alopecia
The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
research Female Hirsutism: Pathophysiological Considerations and Therapeutic Implications
Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.
research Extensive Alopecia Areata: Not Necessarily Recalcitrant to Therapy
Some people with severe, long-lasting baldness responded well to a specific combination treatment.
research Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors
Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.
research Differential Activity of 2-Methylene-19-Nor Vitamin D Analogs on Growth Factor Gene Expression in Rhino Mouse Skin and Comparison to All-Trans Retinoic Acid
Some vitamin D analogs can thicken skin and reduce pore size like a common acne treatment, with one analog also affecting skin growth factors.
research Scalp Needle Mesotherapy as a Method Supporting the Treatment of Alopecia
Scalp needle mesotherapy can effectively treat hair loss and improve hair growth.
research The Pediatric Origins of Polycystic Ovary Syndrome
Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.
research Comparison of Finasteride (Proscar) and Serenoa Repens (Permixon) in the Inhibition of 5-Alpha Reductase in Healthy Male Volunteers
Finasteride works better than Permixon in reducing dihydrotestosterone levels.
research Design of Finasteride-Loaded Nanoparticles for Potential Treatment of Alopecia
Finasteride-loaded nanoparticles may help treat alopecia.
research Self-Microemulsifying Systems of Finasteride with Enhanced Oral Bioavailability: Multivariate Statistical Evaluation, Characterization, Spray-Drying and In Vivo Studies in Human Volunteers
Improved Finasteride delivery for hair loss treatment.
research Combination of Herbal Extracts and Platelet-Rich Plasma Induced Dermal Papilla Cell Proliferation: Involvement of ERK and Akt Pathways
Herbal extracts and platelet-rich plasma together may help increase hair growth by making certain cells grow more, through specific cell growth pathways.
research Effect of Finasteride on Behavioral Arousal and Somatosensory Evoked Potentials in Fetal Sheep
Finasteride may affect fetal brain development and increase arousal, but more research is needed for safety confirmation.
research Herbal Extracts Induce Dermal Papilla Cell Proliferation of Human Hair Follicles
Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.
research Experimental, Molecular Docking Investigations and Bioavailability Study on the Inclusion Complexes of Finasteride and Cyclodextrins
Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.
research The Effect of Finasteride and Dutasteride on the Synthesis of Neurosteroids by Glioblastoma Cells
Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.
research Spontaneous Improvement of Cronkhite-Canada Syndrome in a Postpartum Female
A young woman's Cronkhite-Canada syndrome improved on its own after she gave birth.
research Androgenic Effect of Testosterone and Its Metabolites in Relation to Their Biotransformation in the Skin
Testosterone and some of its forms can strongly stimulate oil gland growth in skin.
research Development and Evaluation of Finasteride-Loaded Ethosomes for Targeting the Pilosebaceous Unit
Finasteride-loaded ethosomes improve hair loss treatment by targeting pilosebaceous unit.
research Development of a Liquid Chromatography/Mass Spectrometry-Based Inhibition Assay for Screening Steroid 5-Alpha Reductase in Human and Fish Cell Lines
A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.
research Cosmetic Procedures in the Treatment of Alopecia
Some cosmetic procedures show promise for treating hair loss, but more research is needed to confirm their safety and effectiveness.
research Dissolvable Microneedles Loaded with Ginsenoside Rg3 Liposome: A Transdermal Delivery Approach for Alopecia Treatment
Dissolvable microneedles with Ginsenoside Rg3 can help treat hair loss by improving drug delivery and stimulating hair growth.