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Optimizing drug delivery to hair follicles is crucial for effective treatment.

Terbinafine quickly builds up in skin and hair, staying effective for over 3 weeks.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Mutations in three genes cause Uncombable Hair Syndrome, leading to frizzy hair that can't be combed flat.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Trichotillomania involves hair pulling and can be treated with therapy and medication.

Nanoparticles can deliver vaccines through hair follicles, triggering immune responses and providing protection.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

Alopecia is a key indicator of thallium poisoning.

Most COVID-19 patients in hospitals have androgenetic alopecia, more in men, suggesting a link between androgen sensitivity and severe COVID-19 symptoms.

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Most women with PCOS have high levels of male hormones, and free testosterone is the best marker for this.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

The conclusion is that the increasing use of drugs for lifestyle reasons is a complex issue influenced by corporate profit, consumer behavior, and the medicalization of everyday life, with potential negative effects on personal well-being.

Ectodysplasin inhibits Wnt signaling to help form hair follicles.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Red light therapy at 655 nm significantly improved hair growth in men with hair loss.

A 300 mg monthly pulse of prednisolone effectively and safely treats widespread alopecia areata.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.