7 citations
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February 2016 in “Dermatology and therapy” This study found that t-flavanone may promote hair growth in people with androgenic alopecia by enhancing hair anchoring strength and upregulating desmoglein expression in hair follicles over 30 weeks.
19 citations
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February 2016 in “Journal of The American Academy of Dermatology” This study found that the presence of CD3(+) T-cells within empty follicular fibrous tracts is a reliable indicator for diagnosing diffuse alopecia areata instead of pattern hair loss.
December 2025 in “Journal of Investigative Dermatology” Immune system issues may contribute to female pattern hair loss.
June 2026 in “American Journal of Dermatopathology” This review describes various T-cell-mediated alopecias characterized by distinct lymphocytic patterns and explores their pathophysiology. It highlights the role of CD8+ and regulatory T cells, the JAK/STAT pathway, and stem cell niches, contributing to understanding and potentially addressing these hair loss conditions.
September 2020 in “Hair transplant forum international” This article memorializes Dr. O'Tar T. Norwood and highlights his contributions to the field of hair restoration surgery; it does not report new research findings.
25 citations
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January 2006 in “British Journal of Dermatology” This study found that finasteride decreases DHT/T levels more significantly in the vertex scalp hair than in the occipital hair of patients with male pattern baldness.
20 citations
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August 2009 in “Journal of The European Academy of Dermatology and Venereology” This study found that the occipital scalp is significantly involved in female pattern hair loss, with some patients showing clinically visible alopecia.
17 citations
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July 2003 in “Metabolism-clinical and Experimental” This study found that young women with female-pattern hair loss exhibit increased testosterone production rates while dihydrotestosterone production rates remain within or below the normal range.
10 citations
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November 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reported higher dihydrotestosterone and testosterone levels in balding Korean and Caucasian subjects compared to non-balding controls, with variations suggesting racial differences in androgen metabolism.
July 2026 in “Journal of Cutaneous and Aesthetic Surgery” This study found that trichoscopic quantitative parameters reliably indicate the severity of female pattern hair loss and complement the Sinclair scale by offering a more objective and reproducible grading system.
November 2022 in “Journal of Investigative Dermatology” This study suggests that vellus to terminal hair follicle reconversion can occur in male pattern androgenetic alopecia using an in vivo model with minoxidil and platelet-rich plasma treatment.
August 2021 in “Journal of The American Academy of Dermatology” This article discusses metabolomics in the context of finasteride treatment for male pattern baldness and reports no new clinical results.
January 2026 in “Journal of Investigative Dermatology” Female-pattern hair loss may involve an autoimmune-like process, suggesting new treatment options.
July 2025 in “Journal of Investigative Dermatology” Immune system changes may contribute to female pattern hair loss.
November 2021 in “CRC Press eBooks” This article reviews the characteristics and presentation of fibrosing alopecia in a pattern distribution, a form of scarring alopecia similar to androgenetic alopecia and lichen planopilaris, but provides no new clinical findings.
March 2023 in “Journal of Cosmetic Dermatology” This case report illustrates that fibrosing alopecia in a pattern distribution may be misdiagnosed as androgenetic alopecia due to similar hair loss patterns, but distinctive trichoscopic and histopathologic features help differentiate it.
October 2020 in “International Journal of Research in Dermatology” In this study, adding platelet-rich plasma to minoxidil and finasteride treatment for patterned hair loss improved hair outcomes with minimal side effects compared to using minoxidil and finasteride alone.
332 citations
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June 1994 in “Archives of Dermatology” This study found that progressive frontal hairline recession in postmenopausal women may exhibit features similar to fibrosing alopecia, with histologic similarities to lichen planopilaris but lacking lesions of lichen planus.
32 citations
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January 1990 in “Clinical Endocrinology” This study found that women with female pattern androgenic alopecia have significantly higher levels of certain androgens and androgen sulfates compared to normal premenopausal women, suggesting markers for diagnosis and treatment efficacy.
July 2025 in “Cell & Bioscience” Specific immune cells and pathways contribute to hair follicle inflammation and hair loss, suggesting potential treatments for lichen planopilaris.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study describes alopecia areata as a long-term, immune-mediated disorder characterized by non-scarring hair loss, often occurring in genetically predisposed individuals and possibly triggered by T-cell-mediated inflammation, environmental stressors, and genetic factors.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study explains that alopecia areata, a long-term immune-mediated disorder causing patchy baldness, results from an immunological attack on hair follicles, often in genetically predisposed individuals, with a complex mix of immunological, environmental, and genetic factors involved in its development.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This source explores alopecia areata, an immune-mediated disorder causing patchy hair loss due to immunological attacks on hair follicles, with a complex interaction of genetic, environmental, and immunological factors, particularly T-cell-mediated inflammation, contributing to its onset.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this research, the authors describe alopecia areata as a long-term, immune-mediated disorder that causes non-scarring hair loss due to an immunological attack on hair follicles, often occurring in genetically predisposed individuals and manifesting in childhood or early adulthood.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This abstract explains that alopecia areata is an immune-mediated condition causing non-scarring hair loss, typically in genetically predisposed individuals, with its etiology linked to immune dysregulation, environmental stressors, and genetic factors.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This source describes alopecia areata as a long-term, immune-mediated disorder causing non-scarring hair loss, often starting in childhood or early adulthood due to genetic predisposition and an immunological attack on hair follicles.
4 citations
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April 2020 in “Facial Plastic Surgery Clinics of North America” This article reviews the comprehensive approach needed for hair restoration in women, including preoperative evaluations, distinguishing scarring alopecias, and managing postoperative hair shock loss, but reports no new clinical findings.
This study found significant differences in facial heat distribution patterns among different types of alopecia, with androgenic, areata, and telogen types showing a T-type pattern, while seborrheic alopecia showed a diffused pattern.
10 citations
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January 2008 in “Biological and Pharmaceutical Bulletin” This study found that trans-3,4'-Dimethyl-3-hydroxyflavanone reduces active TGF-beta2 levels in human keratinocytes, suggesting it may enhance hair growth by suppressing the TGF-beta2 activation pathway.
137 citations
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July 2004 in “Journal of The American Academy of Dermatology” This study observed that triple horizontal scalp biopsies provided a more accurate diagnosis of female pattern hair loss in women than a single horizontal biopsy, especially for those with advanced hair loss.