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Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.

Finasteride safely lowers DHT levels without affecting testosterone.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Testosterone is crucial for development, growth, and various body functions in mammals.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

Finasteride helps induce ovulation in nonresponder PCOS women.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

The normal human prostate does not significantly affect blood DHT levels.

Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.

Hormone levels in hair vary across the head, with the highest concentration of a key hormone linked to hair loss at the top.

Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.

Early onset hair loss linked to genetics and androgen levels.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

Finasteride doesn't affect ovulation in normal women.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Testosterone helps human pancreatic cells increase insulin release.

Low doses of BPA can increase prostate growth and change hormone levels in adult rats.

Higher DHT levels are linked to fewer hypogonadism symptoms in men with normal testosterone levels.

Researchers developed a reliable way to measure hormones in urine, showing that a baldness treatment doesn't change hormone levels.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

New genes and pathways are important for testosterone production and male sexual development.