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FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

Wnt5a may contribute to psoriasis by reducing skin cell growth, blocking skin cell maturation, and increasing inflammation.

Intralesional chemotherapy with 5-fluorouracil and methotrexate may worsen keratoacanthoma-type skin cancer in transplant patients.

PRP helps skin heal, possibly through special cells called telocytes.

The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.

A peptide known for reducing wrinkles also effectively inhibits an enzyme linked to skin inflammation and acne.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

The gene Msx2 is crucial for hair follicle regeneration during wound healing.

Old treatments for other skin conditions showed promise for hair regrowth in mice with a hair loss condition.

Acute leukemias with the Philadelphia chromosome may be biphenotypic, and identifying this is important for proper treatment.

Some multiple sclerosis treatments may trigger hair loss conditions like alopecia areata.

High TSPEAR levels in colorectal cancer predict worse outcomes.

High TSPEAR levels in colorectal cancer predict worse outcomes.

The document concludes that new treatments for skin conditions are complex but effective, including spironolactone for female hair loss and propranolol for infantile hemangiomas.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

Testosterone may slow down wound healing and increase inflammation.

The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.

Low-level laser treatment helped rats regrow hair faster after chemotherapy.

Cyclosporine A promotes hair growth and prolongs the active growth phase in human hair follicles, but may work differently than in rodents.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Fat tissue extract may help treat vitiligo by reducing cell stress and promoting skin repair.

Proteoglycans are important for hair growth, and a specific treatment can help reduce hair loss.

Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.

Activating the Nrf2 pathway reduces inflammation and cell activation in human hair follicles, suggesting a potential treatment for certain hair loss conditions.

A man developed a skin reaction from metronidazole, which improved after stopping the drug and starting steroids.

Electric pulse treatments for breast cancer show promise in being safer and more effective, with fewer side effects.