Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the various roles of RANK signaling in bone remodeling, immune function, and epithelial differentiation, highlighting its potential involvement in cancer mechanisms; it reports no new clinical results.

This study found that osteopontin mRNA is abundantly expressed in dermal papilla cells during the catagen phase of hair growth in rats, suggesting a role in this phase.

This report describes a rare case of alopecia areata coexisting with primary scarring alopecia, diagnosed through detailed trichoscopic investigation, highlighting the importance of comprehensive examination for accurate diagnosis.

This review explores the association between alopecia and thyroid autoimmune disease, also highlighting a linked increased risk of thyroid cancer, but presents no new clinical findings.

This review summarizes current evidence on the use of contact immunotherapy, excluding alopecia areata, for various skin diseases, discussing its safety, efficacy, and the underlying mechanisms as reported from studies in the PubMed database.

This article discusses the characteristics of alopecia areata, including its reversible hair loss pattern and uncertain causes, but reports no new clinical findings.

This review outlines the proposed theories behind the development of alopecia areata, emphasizing the autoimmune process involving lost immune privilege in hair follicles, and stresses the need to pinpoint specific pathogenic mechanisms for potential treatments.

Men with early balding should be checked for metabolic syndrome, as there's a link between the two.

This review discusses how epidermal Langerhan's cells and dermal cells may influence keratinocyte environments, potentially aiding in the formation of stem cell niches and cellular variety in the basal layer, without providing novel results.

This article reviews lichen planopilaris, a chronic scarring alopecia, and explores recent treatment developments, but it reports no new clinical results.

This review discusses hair follicle stem cells for wound healing and reports no new clinical results, noting their potential but emphasizing the need for further understanding and safety in clinical applications.

This study found that tdDPC-EVs significantly improved wound healing by enhancing angiogenesis through the KLF4/VEGFA axis, offering advantages over traditional DPC-EVs.

This study introduced hydrogel microneedles loaded with palladium nanoparticles, which utilize the inherent cytotoxicity of polyethyleneimine to enhance the effectiveness of doxorubicin in treating melanoma, achieving a tumor inhibition rate of up to 98% in a murine model.

This review suggests that the mTOR signaling pathway may play a significant role in hair follicle health by influencing the effects of Vitamin D receptor deficiency, potentially contributing to hair follicle damage and related hair loss conditions.

This study found that ultraviolet radiation causes significant damage to human hair follicles, including increased cell apoptosis and oxidative DNA damage, but this damage may be mitigated by topical caffeine.

This review summarizes the current understanding of Wnt signaling in relation to its roles in tissue regeneration and cancer progression and discusses recent medical advancements targeting this pathway for therapeutic purposes.

This review summarizes fundamental concepts and recent advancements in hair follicle biology, including insights from mouse models into broader molecular and cellular processes relevant to regeneration and development.

This study suggests that programmed cell death plays a crucial role in shaping the structure of the human epidermis and its appendages during development.

This review discusses the mechanisms and potential therapeutic benefits of mesenchymal stromal cell-derived extracellular vesicles delivered via biomaterials, but reports no new clinical results.

This review explores the potential (neuro-)endocrine influences on hair follicle epithelial stem cell biology and emphasizes the need for more systematic research, but it provides no new empirical results.

This study found that micro-current electrical stimulation may promote hair growth in human hair follicle-derived papilla cells and a mice model by enhancing cell proliferation, migration, and activating key growth pathways.

This study found that Sox10 may play a role in early hair follicle development and cycling, as it is expressed in specific regions of the hair follicle during different phases of the hair cycle in mice.

This review discusses the role of dermal macrophages in stress-induced hair regeneration and reports no new clinical findings, highlighting the need for further research into macrophage dynamics for potential hair loss therapies.

This study investigated the hair growth-promoting effect of topical nebivolol cream in mice, but the abstract does not provide specific results or conclusions.

This study suggests that macrophages play a more substantial role in the pathogenesis of Lichen planopilaris compared to Frontal fibrosing alopecia, as indicated by increased CD68+ cells in Lichen planopilaris.

This review discusses the evolving understanding of epithelial stem cells, noting how new models challenge old assumptions and suggesting multiple stem cell populations contribute differently to skin and hair follicle regeneration.

This article reviews potential pathomechanisms of vitiligo, emphasizing membrane alterations involving cholesterol and cardiolipin, but reports no new clinical findings.

This review discusses recent advancements in hair follicle regeneration technologies, including the authors' own development of functional hair regeneration through bioengineered follicle germ transplantation, but reports no new clinical results.

This article provides a detailed analysis of immunosuppressive medications in transplant patients and discusses the increased risk of skin cancer, but it reports no new experimental results.

This review examines the origins and mechanisms of tumor initiation in common skin cancers, but does not present new experimental findings; it emphasizes the need for further research on cancer stem cells.