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Melanocyte-associated antigens may play a key role in alopecia areata and could be targets for new treatments.

Pure carbon nanotubes are safe for mice, but impure ones cause immune issues and hair loss.

Apoptosis is crucial for healthy skin and treating skin diseases.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

Newborn screening and gene therapy are expected to improve outcomes for Omenn syndrome patients.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Activating TLR5 in the gut can extend lifespan and improve health in aged mice.

Pantethine may boost the immune system's ability to fight sarcoma.

Different immune cells like platelets, mast cells, neutrophils, macrophages, T cells, B cells, and innate lymphoid cells all play roles in skin wound healing, but more research is needed due to inconsistent results and the complex nature of the immune response.

T-regulatory cells are important for skin health and can affect hair growth and reduce skin inflammation.

Significant progress and collaborations in stem cell research and regenerative medicine were made, including advancements in hair growth, cancer therapies, and treatments for neurological disorders.

Alopecia areata is an autoimmune disease where T cells attack hair follicles.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.

ILC1-like cells can independently cause alopecia areata by affecting hair follicles.

UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

ADM scaffolds help skin heal by promoting a healing-type immune response.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

iNKT cells can help prevent and treat alopecia areata by promoting hair regrowth.

Fetal skin has unique immune cells different from adult skin.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.

A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.