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Taking Advantage of Phenotype Variability in a Local Animal Genetic Resource: Identification of Genomic Regions Associated with the Hairless Phenotype in Casertana Pigs

research Taking Advantage of Phenotype Variability in a Local Animal Genetic Resource: Identification of Genomic Regions Associated with the Hairless Phenotype in Casertana Pigs

16 citations, April 2018 in “Animal Genetics”

Researchers found two genes that may explain why some Casertana pigs don't have hair.

Treatment of Male Rats with Finasteride, an Inhibitor of 5alpha-Reductase Enzyme, Induces Long-Lasting Effects on Depressive-Like Behavior, Hippocampal Neurogenesis, Neuroinflammation, and Gut Microbiota Composition

research Treatment of Male Rats with Finasteride, an Inhibitor of 5alpha-Reductase Enzyme, Induces Long-Lasting Effects on Depressive-Like Behavior, Hippocampal Neurogenesis, Neuroinflammation, and Gut Microbiota Composition

37 citations, September 2018 in “Psychoneuroendocrinology”

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

research CCR5 Blockade Shows Prevention of Alopecia Areata Development as Well as Improvement of Alopecia Areata

September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

Blocking CCR5 can prevent and improve hair loss in alopecia areata.

Epidermal Keratinocytes Initiate Wound Healing and Pro-Inflammatory Immune Responses Following Percutaneous Schistosome Infection

research Epidermal Keratinocytes Initiate Wound Healing and Pro-Inflammatory Immune Responses Following Percutaneous Schistosome Infection

39 citations, January 2015 in “International journal for parasitology/International Journal for Parasitology”

Epidermal keratinocytes start wound healing and inflammation after schistosome infection.

research Topical Application of Oleuropein Induces Anagen Hair Growth in Telogen Mouse Skin

32 citations, June 2015 in “PLOS ONE”

Olive leaf compound oleuropein helps grow hair in mice.

Activin Controls Skin Morphogenesis and Wound Repair Predominantly via Stromal Cells and in a Concentration-Dependent Manner via Keratinocytes

research Activin Controls Skin Morphogenesis and Wound Repair Predominantly via Stromal Cells and in a Concentration-Dependent Manner via Keratinocytes

81 citations, September 2005 in “The American journal of pathology”

Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.

research Translational Positioning of Janus Kinase (JAK) Inhibitors in Alopecia Areata

11 citations, April 2015 in “EBioMedicine”

JAK inhibitors may help treat Alopecia Areata but need careful monitoring due to side effects.

Loss of Langerhans Cells in Scar Lesion of Lichen Planopilaris Is Caused by Downregulation of Integrin αvβ6 in the Epidermal Keratinocytes

research Loss of Langerhans Cells in Scar Lesion of Lichen Planopilaris Is Caused by Downregulation of Integrin αvβ6 in the Epidermal Keratinocytes

September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

Scarred skin in lichen planopilaris loses immune cells due to a decrease in a specific protein in skin cells.

research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men

31 citations, January 2017 in “Advances in Experimental Medicine and Biology”

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

research Retinoids Putting the 'A' in Alopecia

7 citations, January 2013 in “Journal of Investigative Dermatology”

Vitamin A may influence hair loss conditions like alopecia, but more research is needed to understand how.

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