research Beta-Catenin–Dependent Wnt Signaling: A Pathway in Acute Cutaneous Wounding
The study found that a specific signaling pathway helps skin wounds heal faster but may lead to larger scars.
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research Hair Growth in a Patient with Alopecia Areata on Tocilizumab
A woman with alopecia regrew her hair after taking a higher dose of tocilizumab.
research Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition
The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
research A Multicomponent Skin-Targeted COVID-19 Vaccine Elicits Robust Humoral and Cellular Immune Responses
The new skin-targeted COVID-19 vaccine creates strong immune responses and could improve vaccination methods.
research Lymphatic Vasculature and Hair Follicle Regeneration
Lymphatic vessels help hair follicles regenerate by interacting with stem cells.
research Application of Mesenchymal Stem Cells for Anti-Senescence and Clinical Challenges
Mesenchymal stem cells could help treat aging-related diseases better than current methods.
research Conversion of the Nipple to Hair-Bearing Epithelia by Lowering Bone Morphogenetic Protein Pathway Activity at the Dermal-Epidermal Interface
Blocking a specific protein signal can make hair grow on mouse nipples.
research Loss of Epidermal Melanin Unit Integrity in Human Skin During Melanoma Genesis
Melanoma development can be linked to the breakdown of skin's melanin-producing units.
research An Open Label Clinical Trial of the JAK Inhibitor Tofacitinib for Alopecia Areata
Tofacitinib helped over half of the patients with severe hair loss regrow at least 50% of their hair.
research Regulated Proenkephalin Expression in Human Skin and Cultured Skin Cells
Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.
research Teriflunomide in Multiple Sclerosis: An Update
Teriflunomide effectively reduces relapses and disability in MS and has a manageable safety profile.
research Clinical Investigation of JAK Inhibitor Tofacitinib in Scarring Alopecias
Tofacitinib may slow hair loss in scarring alopecias but is unlikely to regrow significant hair.
research Bacteria Induce Skin Regeneration
Certain bacteria can enhance skin regeneration.
research Peroxisome Proliferator-Activated Receptors (PPARs) and PPAR Agonists: The Future in Dermatology Therapeutics?
PPAR agonists show promise for skin conditions but need more research before being a main treatment.
research Adult Skin Acute Stress Responses to Short-Term Environmental and Internal Aggression from Exposome Factors
Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.
research Methotrexate for Generalized Pustular Psoriasis in a 2-Year-Old Child
Methotrexate effectively treated a 2-year-old's generalized pustular psoriasis without side effects.
research Focal Hypertrichosis During Topical Tacrolimus Therapy for Childhood Vitiligo
An 8-year-old girl with vitiligo developed extra hair growth on her knee after using tacrolimus ointment.
research Systemic Treatment for Alopecia Areata
Effective treatments for severe alopecia areata are still lacking.
research Fox Fordyce Disease in a Prepubertal Girl
A 10-year-old girl with Fox Fordyce disease improved with treatment, suggesting the disease can occur before puberty and might be underdiagnosed in young girls.
research Geographic Tongue in Two Children with Nonpustular Psoriasis
Fox Fordyce disease might be more common in prepubertal girls than thought and can be managed with treatment.
research Immunomodulators in the Treatment of Cutaneous Lymphoma
Immunomodulatory therapies are effective for treating cutaneous lymphoma, particularly in early stages.
research Cutaneous Mastocytosis in Children: An Indian Experience
Fox Fordyce disease can occur in prepubertal girls and may be underdiagnosed.
research Decreased Serum Ferritin and Alopecia in Women
Low serum ferritin levels are linked to hair loss in women.
research An Accessible Pharmacodynamic Transcriptional Biomarker for Notch Target Engagement
Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.
research Small Molecule Inhibitors and Inflammatory Skin Diseases
New drugs targeting the JAK-STAT pathway show promise for treating inflammatory skin diseases.
research Alopecia Areata In Infants: Is It Uncommon?
Alopecia areata in infants may be more common than previously thought.
research Melatonin: A Cutaneous Perspective on Its Production, Metabolism, and Functions
Melatonin may benefit skin health and could be a promising treatment in dermatology.
research Alopecia Areata: A Multifactorial Autoimmune Condition
Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
research Linking Diet to Acne Metabolomics, Inflammation, and Comedogenesis: An Update
Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.
research Resting No More: Redefining Telogen, the Maintenance Stage of the Hair Growth Cycle
The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.