research Pharmacological Treatment of Alopecia
Only minoxidil and finasteride are FDA-approved for hair loss, with other treatments available but less effective or with side effects.
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research Organ Regeneration Based on Developmental Biology: Past and Future
Scientists have made progress in growing mini-organs and regenerating parts of the skin, with plans to treat hair loss in a future trial.
research Red Blood Cell Folate Level in Patients with Alopecia Areata
Red blood cell folate levels are reliable indicators of long-term folate status in alopecia areata patients.
research RANKL Induces Organized Lymph Node Growth by Stromal Cell Proliferation
RANKL causes lymph nodes to grow by making certain cells multiply.
research Generating Detailed Intercellular Communication Patterns in Psoriasis at the Single-Cell Level Using Social Networking, Pattern Recognition, and Manifold Learning Methods to Optimize Treatment Strategies
New insights into cell communication in psoriasis suggest innovative drug treatments.
research Differential Effects of Wnt5a on the Proliferation, Differentiation, and Inflammatory Response of Keratinocytes
Wnt5a may contribute to psoriasis by reducing skin cell growth, blocking skin cell maturation, and increasing inflammation.
research Roles of Melatonin in Goat Hair Follicle Stem Cell Proliferation and Pluripotency Through Regulating the Wnt Signaling Pathway
Melatonin helps goat hair stem cells grow and maintain their ability to become different cell types.
research Stem Cell Heterogeneity and Plasticity in Epithelia
Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
research Presence of Mast Cells and Mast Cell Degranulation in Scalp Biopsies of Telogen Effluvium
The study suggests that mast cells might be involved in the hair loss condition telogen effluvium and could be a target for treatment.
research Prolactin and the Skin: A Dermatological Perspective on an Ancient Pleiotropic Peptide Hormone
Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.
research A Neuroendocrinological Perspective on Human Hair Follicle Pigmentation
Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
research Mesenchymal Stem Cells for the Treatment of Skin Diseases
Mesenchymal stem cells show promise for treating various skin conditions and may help regenerate hair.
research CD4+CD25+FoxP3+ Regulatory Tregs Inhibit Fibrocyte Recruitment and Fibrosis via Suppression of FGF-9 Production in the TGF-β1 Exposed Murine Lung
Special immune cells called Tregs can help prevent lung scarring by blocking a specific growth factor.
research Function of KLF4 in Stem Cell Biology
KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
research Immune Niches for Hair Follicle Development and Homeostasis
Immune cells are crucial for hair growth and preventing hair loss.
research An Unusual Pattern of Alopecia Areata
A man had an unusual type of hair loss that didn't match known patterns and didn't improve with treatment.
research Summary of the Preceding Three Alopecia Areata Research Summits: What’s Past Is Prologue
New treatments and strategies are needed for Alopecia Areata, focusing on immune response and better trial designs.
research Interrelation of Immunity and Tissue Repair or Regeneration
The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.
research Present and Future Use of Exosomes in Dermatology
Exosomes could be key in treating skin conditions and healing wounds.
research Umbilical Cord-Derived Mesenchymal Stem Cell Secretome Promotes Skin Regeneration and Rejuvenation: From Mechanism to Therapeutics
Stuff from umbilical cord stem cells helps skin heal and look younger.
research Controlling Hair Loss by Regulating Apoptosis in Hair Follicles: A Comprehensive Overview
Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.
research Pharmacological Activity Of Cepharanthine
Cepharanthine has many medicinal uses but needs improvement for better effectiveness.
research Umbilical Cord Mesenchymal Stem Cell-Derived Apoptotic Extracellular Vesicles Ameliorate Cutaneous Wound Healing in Type 2 Diabetic Mice via Macrophage Pyroptosis Inhibition
Special particles from umbilical cord stem cells help heal skin wounds in diabetic mice by preventing certain immune cell death.
research Application of Mesenchymal Stem Cells for Anti-Senescence and Clinical Challenges
Mesenchymal stem cells could help treat aging-related diseases better than current methods.
research Trichoblastoma with Sebaceous and Sweat Gland Differentiation
A rare benign skin tumor showed unusual features of sebaceous and sweat glands, important for correct diagnosis.
research Single-Cell Sequencing Reveals Differential Cell Types in Skin Tissues of Liaoning Cashmere Goats and Key Genes Potentially Related to the Fineness of Cashmere Fiber
Certain genes are linked to the quality of cashmere in goats.
research The Pathogenesis of Alopecia Areata in Rodent Models
Alopecia Areata is an autoimmune disease affecting hair follicles, influenced by genetic and environmental factors, with rodent models being essential for research.
research Endogenous Retinoids in the Hair Follicle and Sebaceous Gland
Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.
research Epidermal Wnt/Beta-Catenin Signaling Promotes Dermal Adipocyte Differentiation During Hair Follicle Morphogenesis and Regeneration
Wnt/beta-catenin signaling in the skin helps fat cell development during hair growth and repair.
research Effects of Natural Herbal Marker Compounds on Human Dermal Papilla Cell Growth Regulation
Four natural compounds were found to promote hair growth effectively.