research Adult Epidermal Notch Activity Induces Dermal Accumulation of T Cells and Neural Crest Derivatives Through Upregulation of Jagged 1
Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
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research Immune Cell Regulation of the Hair Cycle
Immune cells affect hair growth and could lead to new hair loss treatments.
research Modeling Cell-Cell Communication for Immune Systems Across Space and Time
The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.
research The Functional Relevance of the Type 1 Cytokines IFN-γ and IL-2 in Alopecia Areata of C3H/HeJ Mice
IFN-γ and IL-2 are important for T cell activation in hair loss in mice.
research Regulating Hair Follicle Stem Cells
Special immune cells called Treg cells are important for maintaining and regenerating hair by activating a specific growth signal in hair stem cells.
research Towards a Consensus Potency Assay for Mesenchymal Stromal Cells: A Matrix Analysis of Cell Source, Donor Variability, and Inflammatory Stimuli to Refine Surrogate Markers of Immunomodulation
ATIR101 improves survival in stem cell transplant patients; Australian stem cell treatment decisions are influenced by regulation changes.
research Sphingolipid Metabolism Orchestrates the Establishment of the Adult Hair Follicle Stem Cell Niche to Control Skin Homeostasis
A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.
research TNC+ Fibroblasts Involved in Skin Inflammation via Neuro-Immune Interactions with T Cells
TNC+ fibroblasts play a key role in skin inflammation by interacting with T cells.
research Faculty Opinions Recommendation of Identification of Drug-Specific Public TCR Driving Severe Cutaneous Adverse Reactions
Researchers found a specific T cell receptor linked to severe drug reactions like Stevens-Johnson syndrome when patients take carbamazepine.
research Cell-Cell Interaction in the Hair Follicle Niche in Androgenetic Alopecia
New drug targets for hair loss treatment were identified by studying cell interactions in hair follicles.
research A Family Business: Stem Cell Progeny Join the Niche to Regulate Homeostasis
Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
research Role of Cytotoxic T Cells in Chronic Alopecia Areata
Cytotoxic T cells cause hair loss in chronic alopecia areata.
research Controlled Delivery of T-box21 Small Interfering RNA Ameliorates Autoimmune Alopecia in a C3H/HeJ Mouse Model
Controlled delivery of specific RNA and IL-4 restored hair growth in mice with autoimmune alopecia.
research Clinical and Laboratory Evaluation of AIDS Trichopathy
People with HIV and low T cell counts have more hair and scalp problems.
research The Promise and Challenges of Cell Therapy for Psoriasis
Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.
research Disturbance of Immune Microenvironment in Androgenetic Alopecia Through Spatial Transcriptomics
Androgenetic alopecia involves immune cell disruptions, especially increased CD4+ T cells around hair follicles.
research Braicitinib Treatment Reduced the Expansion of CD8+ T Cells in C3H Mice With Skin Grafts-Induced Alopecia Areata
Baricitinib treatment helped reduce hair loss symptoms in mice by decreasing inflammation-related immune cells.
research Surgical Approaches for Repigmenting Vitiligo 2.0
Assessing CD8+ T cell levels before surgery may improve vitiligo treatment outcomes.
research Single-Cell Transcriptomics Reveals Distinct Molecular Programs in Folliculotropic Mycosis Fungoides
Folliculotropic mycosis fungoides has unique molecular features and cell interactions that could guide targeted therapy.
research Cell Population Dynamics in Wound-Induced Hair Follicle Neogenesis Model
Non-immune dermal cells dominate, epidermal cells increase after day 9, and certain immune cells persist beyond inflammation in wound-induced hair follicle regeneration.
research Resident Memory T Cells in Autoimmune Skin Diseases
Certain immune cells contribute to skin autoimmune diseases, and some treatments can reverse hair loss in these conditions.
research The Contributory Roles of Th17 Lymphocyte and Cytotoxic T Lymphocyte at the Hair Bulge Region and Hair Bulb Area in Chronic Alopecia Areata Patients
Certain immune cells contribute to severe hair loss in chronic alopecia areata, with Th17 cells possibly having a bigger impact than cytotoxic T cells.
research Follicular Mycosis Fungoides Mimicking a Cutaneous B-Cell Lymphoproliferative Disorder
Follicular mycosis fungoides can look like a B-cell lymphoma, making diagnosis difficult.
research Spectrum of Mucocutaneous Manifestations in HIV-Infected Patients and Its Correlation with CD4 Lymphocyte Count
HIV patients with lower CD4 T cell counts often have more skin problems.
research The Expanding Impact of T-Regulatory Cells in Skin Health
T-regulatory cells are important for skin health and can affect hair growth and reduce skin inflammation.
research TLR9 Activation in Large Wound Induces Tissue Repair and Hair Follicle Regeneration via γδT Cells
Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.
research Impact of the COVID-19 Pandemic on Tertiary Care University Dermatology Outpatient Clinic and Dermatology Procedures
The COVID-19 pandemic led to fewer patient visits, more visits by older adults, an increase in cutaneous T-cell lymphoma cases, and a rise in noncosmetic procedures at a dermatology clinic.
research Tissue Resident and Follicular Treg Cell Differentiation Is Regulated by CRAC Channels
CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
research Effects of Dihydrotestosterone on Rat Dermal Papilla Cells In Vitro
Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.
research Tissue Resident Foxp3+ Regulatory T Cells: Sentinels and Saboteurs in Health and Disease
Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.