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PPARγ is crucial for skin health but can have both beneficial and harmful effects.

Sex hormones, especially androgens, play a key role in causing acne.

The skin produces and processes hormones, affecting both local and overall body functions.

TREM2 macrophages and unsaturated lipids contribute to acne inflammation.

Adipokines affect skin health and could be targeted for treating skin diseases.

Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.

Cell-based models help test if cosmetic ingredients really work for hair growth and skin health.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

Hemp is a promising ingredient for skin products due to its healing and soothing properties.

CBD may improve skin and hair health, but its effective use and safety need more research.

Paris polyphylla saponins may effectively treat acne due to their antibacterial and anti-inflammatory properties.

Metformin might help treat certain skin conditions, but more research is needed.

Adult acne is often related to hormonal disorders, especially in women, and may need long-term treatment involving specialists.

Green tea extract increases lipid production in human sebaceous gland cells.

Shrinking of oil glands in the skin is a key sign of hair loss linked to TNF inhibitor drugs and may improve if the treatment is stopped.

The enzymes Tet1, Tet2, and Tet3 are important for the development of hair follicles and determining hair shape by controlling hair keratin genes.

Researchers created human cells that can turn into sebocytes, which may help study and treat skin conditions like acne.

Psoriasis lesions have fewer and smaller oil glands, which might affect the condition's development.

TGFβ signaling prevents sebaceous gland cells from producing fats.

Androgens cause oil-producing skin cells with androgen receptors to mature and produce more oil.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Acne is a chronic disease linked to various systemic conditions and has significant psychological and social effects.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Blocking a specific enzyme can reduce the negative impact of stress hormones on hair growth cells.

The Siah1 and Siah2 genes are active in mouse skin development and hair growth, especially right after birth.

Certain miRNAs might be involved in a hair loss condition called frontal fibrosing alopecia and could possibly help in its diagnosis.

The study found that sweat glands normally suppress immune responses, but this is disrupted in certain skin diseases, possibly contributing to their development.

Finasteride helps female-pattern hair loss.