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Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

Green tea extract increases lipid production in human sebaceous gland cells.

Sebocytes play a key role in controlling androgen levels in human skin.

Blocking SCD1 in the skin with XEN103 shrinks sebaceous glands in mice.

The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Lotus corniculatus seed extract reduces oily skin by decreasing sebum production.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Indian Hedgehog helps control skin cell growth and protects against aggressive skin cancer.

Scientists created a 3D skin model to study a chronic skin disease and test treatments.

Cidea is essential for proper lipid storage and secretion in sebaceous glands, affecting skin and hair health.

Activating TRPV3 reduces skin oil production and increases inflammation, potentially causing dry skin issues.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

Better hair loss models needed for research.

Paris polyphylla saponins may effectively treat acne due to their antibacterial and anti-inflammatory properties.

The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.

Lack of TG2 increases fat storage and lowers cell cleanup in skin oil cells.

Oleoylethanolamide (OEA) safely boosts fat production in skin cells and may help treat dry skin and reduce inflammation.

The endocannabinoid system affects oil production and inflammation in skin cells.

The 3D-SeboSkin model effectively simulates Hidradenitis suppurativa and is useful for future research.

Scarred skin in lichen planopilaris loses immune cells due to a decrease in a specific protein in skin cells.

Blocking 11β-HSD1 can lessen the harmful effects of glucocorticoids on hair growth cells.

Blocking a specific enzyme can reduce the negative impact of stress hormones on hair growth cells.

Dermal Papilla Cells grown in 3D and with stem cells better mimic natural hair growth conditions than cells grown in 2D.

The role of γδT-cells in causing alopecia areata remains unclear.

Researchers created human cells that can turn into sebocytes, which may help study and treat skin conditions like acne.

DHT reduces a cell's ability to promote hair growth, while 3D culture without DHT improves it.

Avicennia Marina extract and avicequinone C can reduce hair loss hormone production and increase hair growth factors, suggesting they could be used to treat androgenic alopecia.