January 2019 in “International Journal of Dermatology” This study found a higher prevalence of metabolic syndrome in males with androgenetic alopecia compared to controls, suggesting a significant association between the two conditions.
February 2017 in “Clinical dermatology open access journal” This study found a strong association between insulin resistance and early androgenetic alopecia in males, with insulin resistance increasing alongside alopecia severity and influenced by factors like smoking.
July 2015 in “Egyptian Journal of Dermatology and Venereology” This study concluded that patients with androgenetic alopecia may have a higher risk of cardiovascular diseases compared to people without this condition.
May 2015 in “Scientific journal of Kurdistan University of Medical Sciences” Men with early-onset baldness may have a higher risk of heart disease.
December 2025 in “Jurnal Kesehatan Tambusai” This study examined the relationship between blood pressure and alopecia in Belitang, finding a significant association with higher blood pressure among those with alopecia and identifying an elevated risk in the Komering ethnic group, suggesting potential genetic factors.
19 citations
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May 1979 in “Archives of internal medicine” Minoxidil effectively lowers blood pressure and initially increases plasma renin activity without raising aldosterone levels.
23 citations
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November 1986 in “Pediatrics” Minoxidil, when used with a diuretic and β-blocking agent, can safely lower blood pressure in most children with severe hypertension due to kidney disease, with minimal side effects.
October 2013 in “Journal of the American College of Cardiology” Blood pressure that doesn't drop at night is linked to worse blood vessel function in people with high blood pressure.
July 2025 in “Journal of Investigative Dermatology” Spironolactone can safely lower blood pressure in patients on other blood pressure medications, but may slightly increase the risk of low blood pressure.
17 citations
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March 1985 in “Journal of The American Academy of Dermatology” Minoxidil can lower blood pressure in some people.
September 2025 in “Journal of the American Academy of Dermatology” Low-dose oral minoxidil does not significantly affect blood pressure in patients with hair loss and hypertension.
September 2025 in “International Journal For Multidisciplinary Research” This study observed that patients with androgenetic alopecia in a western Indian population had a significantly higher prevalence of metabolic syndrome compared to a matched control group, suggesting that individuals with this type of hair loss may benefit from screening for metabolic syndrome.
4 citations
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March 2024 in “Journal of the American Academy of Dermatology” Spironolactone for skin issues rarely causes low blood pressure.
August 2026 in “Journal of Multidisciplinary Healthcare” In this study, no association was found between androgenetic alopecia and increased blood pressure or higher serum aldosterone levels in the examined hospital-based sample from Saudi Arabia.
August 2026 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this study, no significant association between androgenetic alopecia and increased blood pressure or serum aldosterone levels was observed among a small sample of Saudi Arabian men.
4 citations
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February 2024 in “Frontiers in Cardiovascular Medicine” The study observed that Tai Chi and Wuqinxi, when combined with antihypertensive medication, might be particularly effective in lowering systolic and diastolic blood pressure, respectively, suggesting they could be prioritized as treatment options.
1 citations
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August 2025 in “Journal of Diabetes and its Complications” This review found that among young adults with type 1 diabetes, hearing loss prevalence ranged from 22.6% to 48.0% and was associated with age, diabetes duration, and systolic blood pressure, while peridontitis and alveolar bone loss also showed varying prevalence patterns.
January 2023 in “International journal of medical science and health research” This study found that anovulatory PCOS patients were younger, had longer menstrual cycles, and higher systolic blood pressures compared to ovulatory patients.
November 2022 in “Frontiers in Medicine” This study found no direct association between androgenetic alopecia and metabolic syndrome in the Chinese population, though AGA was closely linked with higher systolic blood pressure in men.
5 citations
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January 1988 in “Analytical profiles of drug substances” Minoxidil helps lower blood pressure and can also promote hair growth.
5 citations
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February 1996 in “Clinical pharmacology and therapeutics/Clinical pharmacology & therapeutics” Minoxidil given intravenously caused small changes in diastolic blood pressure and increased heart rate at higher concentrations in patients with high blood pressure.
This study found that metformin significantly improved clinical and hormonal indices in patients with polycystic ovary syndrome compared to pioglitazone, which also effectively controlled some symptoms.
18 citations
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February 2024 in “Nutrients” This study investigated a novel extract from pomegranate byproducts, finding it effective in reducing blood pressure and inflammation in hypertensive rats, comparable to Captopril, while also highlighting the extract's potential to enhance the pomegranate supply chain and environmental benefits.
March 2025 in “International Journal of Scientific Research” This study found that low-dose oral minoxidil effectively increased hair count over 24 weeks with mild reductions in blood pressure and minimal adverse effects among participants, suggesting its potential as a safe treatment for hair loss.
3 citations
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January 2025 in “Journal of Research in Medical Sciences” This study reported that among obese women with PCOS, neither early time-restricted eating (eTRE) alone nor combined with probiotics showed significant improvements in blood pressure, inflammatory markers, oxidative stress, or antioxidant capacity compared to a standard reduced-calorie diet.
October 2024 in “Irish Journal of Medical Science (1971 -)” In this study, TENS of the T6 dermatome over a longer term was explored for its effects on weight, blood pressure, heart rate, and appetite-regulating hormones in obese subjects with moderate obstructive sleep apnea; however, results are not reported in the abstract.
February 2010 in “Journal of The American Academy of Dermatology” A woman with Degos disease managed her condition for nine years with medications and had two healthy pregnancies, while a separate finding suggests a possible link between female pattern hair loss and high blood pressure.
3 citations
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January 2017 in “Journal of cardiovascular pharmacology” This article discusses the challenges in hypertension management, emphasizing the need to reconsider the use of minoxidil and address excess dietary sodium and arteriolar hypertrophy, but reports no new clinical results.
50 citations
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June 2014 in “Experimental and Clinical Endocrinology & Diabetes” This study found that hair cortisol levels increase and testosterone levels decrease with obesity, suggesting that measuring hormones in hair may be a valuable tool in obesity research and clinical practice.
In this study, researchers found that patients with alopecia areata displayed higher systemic inflammatory markers and lower vitamin D levels compared to healthy controls, yet they exhibited similar cardiovascular risk profiles, with no association between inflammation and cardiovascular risk or alopecia severity.