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Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

Trichoscopy helps diagnose and assess the severity of Frontal Fibrosing Alopecia.

Cell aging can be both good and bad for tissue repair.

Certain medications and maintaining adequate iron levels can help manage women's hair loss.

People with Lichen Planus, especially with mucosal involvement, are more likely to have Metabolic Syndrome, which increases their risk for heart disease and diabetes.

Where melanoma is on the body affects survival chances; melanomas on the back of the head are worse, while those on thighs and arms are less severe, and more sun exposure might improve survival.

Some skin disorders might be linked to H. pylori infection, but more research is needed to confirm this.

Alopecia areata, a type of hair loss, is likely an autoimmune disease with a genetic link, but its exact cause is still unknown.

Early stage bald spots are linked to skin inflammation and damage to the upper part of the hair follicle.

Finasteride slows down motherly behavior in first-time pregnant rats.

Minoxidil can lower blood pressure in some people.

Melanoma development can be linked to the breakdown of skin's melanin-producing units.

Certain sex hormones and antiandrogens can either slow down or speed up the growth of human hair follicle cells depending on their concentration.

People with pemphigus vulgaris and pemphigus foliaceus often have smaller sebaceous glands on their scalp.

The AIRE gene variant rs2075876 is linked to a higher risk of alopecia areata in males.

Good nutrition is crucial for healthy hair and can help with hair loss without medication.

The mTOR pathway proteins are altered in the hair follicles of patients with Lichen Planopilaris and Frontal Fibrosing Alopecia.

Dermatologists diagnose and manage melanoma more effectively than general practitioners.

Alopecia areata in US adolescents leads to significant healthcare costs and usage.

A fungus called Epidermophyton floccosum can cause scalp infections.

Machine learning can predict symptoms and quality of life in chronic skin disease patients using smartphone app data, and shows that app use varies with patient characteristics.

People with alopecia areata often have lower vitamin D levels than healthy people.

People with Lichen Planus have thicker carotid artery walls, but it's not solely due to Lichen Planus when other factors are considered.

Hidradenitis suppurativa is a chronic skin condition more common in women, linked to genetics and lifestyle factors, and associated with various other health issues.

People with certain skin diseases have higher levels of the hormone prolactin in their blood.

People with alopecia areata have higher levels of osteopontin, which might be important in the disease's development, but this doesn't relate to how severe the disease is.

The document concludes that management strategies for PCOS are important due to its common occurrence and associated health risks.

Alopecia areata severely impacts quality of life, mental health, and work productivity.