research A Case Report of Thrombotic Thrombocytopenic Purpura Associated with Systemic Lupus Erythematosus: Overlapping Features
Early diagnosis, intensive therapy, and careful follow-up are crucial for managing overlapping TTP and SLE.
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research Benefit and Risk Profile of Tofacitinib for the Treatment of Alopecia Areata: A Systematic Review and Meta-Analysis
Tofacitinib is somewhat effective for alopecia areata, but more research is needed on its safety and long-term effects.
research CRISPR/Cas9-Mediated Disruption of Fibroblast Growth Factor 5 in Rabbits Results in a Systemic Long Hair Phenotype by Prolonging Anagen
Disrupting the FGF5 gene in rabbits leads to longer hair by extending the hair growth phase.
research Exploring the Therapeutic Potential of Herbal Intervention in Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis
Herbal treatments can help manage PCOS symptoms.
research Cyclophosphamide: As Bad as Its Reputation? Long-Term Single Centre Experience of Cyclophosphamide Side Effects in the Treatment of Systemic Autoimmune Diseases
Cyclophosphamide has serious side effects, but long-term follow-up can help manage risks.
research International Society for the Study of Women's Sexual Health Clinical Practice Guideline for the Use of Systemic Testosterone for Hypoactive Sexual Desire Disorder in Women
Testosterone therapy can help postmenopausal women with low sexual desire if monitored carefully.
research Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition
Alopecia areata can be reversed by JAK inhibitors, promoting hair regrowth.
research The Spectrum of Cutaneous Manifestations in Lupus Erythematosus: The Italian Experience
In Italian patients with lupus, the most common skin issue was chronic cutaneous lupus, especially discoid lesions, and nonspecific skin problems occurred in about a third of those with systemic lupus, mainly during active disease.
research Transfollicular Drug Delivery: Is It a Reality?
Hair follicles may soon be used more for targeted and systemic drug delivery.
research A 15-Year-Old Female Patient Diagnosed with Systemic Lupus Erythematosus and Initially Presented with Lupus Nephritis, Cerebritis, and Diffuse Alveolar Hemorrhage
Early recognition and treatment of severe SLE symptoms can improve outcomes.
research Adherence Patterns to Medications and Their Association with Subsequent Hospitalization in Adult Egyptian Patients with Systemic Lupus Erythematosus
Non-adherence to medication in Egyptian SLE patients leads to more hospitalizations and symptoms.
research Cutaneous Lupus Erythematosus: A Review
Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.
research PD-1+ CXCR5− CD4+ T Cells Are Correlated with the Severity of Systemic Lupus Erythematosus
Tph cells are linked to the severity of systemic lupus erythematosus.
research Hair and Systemic Disease
Hair loss can indicate underlying systemic diseases and addressing these can sometimes reverse the hair loss.
research New-Onset Systemic Lupus Erythematosus Beginning as Class V Lupus Nephritis After COVID-19 Vaccination
COVID-19 vaccination may trigger lupus in some people.
research Altered Dermal Fibroblasts in Systemic Sclerosis Display Podoplanin and CD90
Fibroblast changes in systemic sclerosis may help understand disease severity and treatment.
research Nonscarring Alopecia in Systemic Lupus Erythematosus: A Cross-Sectional Study with Trichoscopic, Histopathologic, and Immunopathologic Analyses
Hair loss in lupus patients indicates higher disease activity.
research Systemic Lupus Erythematosus (SLE) in the Eastern Region of Saudi Arabia: A Comparative Study
SLE patients in eastern Saudi Arabia have a generally good prognosis despite multi-organ involvement.
research Catalytic Antibodies in Normal and Systemic Lupus Erythematosus
Catalytic antibodies are early indicators and active participants in the development of systemic lupus erythematosus.
research Lenalidomide for Refractory Cutaneous Manifestations of Pediatric Systemic Lupus Erythematosus
Lenalidomide effectively and safely treats skin symptoms in pediatric lupus, reducing the need for prednisone.
research Satisfaction with Control of Systemic Lupus Erythematosus and Lupus Nephritis: Physician and Patient Perspectives
Both patients and physicians are often dissatisfied with the control of systemic lupus erythematosus and lupus nephritis.
research Antigen Presenting Cells in the Skin of a Patient with Hair Loss and Systemic Lupus Erythematosus
Antigen presenting cells around hair follicles are crucial in SLE-related hair loss.
research Alopecia Areata Flare Patterns in Children and Young Adults on Systemic Tofacitinib
Tofacitinib can regrow hair in alopecia areata patients, but some may experience flares during treatment.
research Dermatological Medications and Local Therapeutics During Pregnancy
Use some skin medications with caution during pregnancy; avoid strong steroids, certain eczema treatments, and systemic retinoids, but many topical treatments and nasal sprays are safe.
research Unilateral Branch Retinal Artery Occlusion in a Patient with Systemic Lupus Erythematosus
Systemic lupus erythematosus treatment can restore vision in patients with retinal artery occlusion.
research Childhood-Onset Systemic Lupus Erythematosus with Trisomy X and Increased Risk for Bone Complications: A Case Report
A girl with lupus and trisomy X has a higher risk of bone problems like avascular necrosis and osteoporosis.
research COVID-19 Vaccination Related Exacerbations of Hair Loss in Patients With Moderate-to-Severe Alopecia Areata on Systemic Therapy
COVID-19 vaccines may rarely worsen hair loss in people with severe alopecia, but the benefits of vaccination still outweigh this risk.
research Treatment of Alopecia Areata and Its Numerous Possibilities: A Literature Review
Alopecia areata treatment should be personalized, using topical or systemic therapies based on severity, with promising options like JAK inhibitors needing more research.
research Anifrolumab Treatment Improves Patient-Reported Quality of Life and Decreases Disease Activity and Corticosteroid Use in Patients with Systemic Lupus Erythematosus: A Qualitative Study in Denmark
Anifrolumab treatment improves quality of life and reduces disease activity and steroid use in SLE patients.
research Systemic Tofacitinib Treatment in Pediatric Patients with Resistant Alopecia Areata
Tofacitinib is a safe treatment for hair loss in children, but long-term use may be needed for best results.