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Exosomes show promise for treating skin diseases and improving skin regeneration.

Drug approvals slowed in 2Q22, but notable drugs like Amvuttra, Camzyos, and Olumiant were approved.

A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Specific immune cells cause alopecia areata and blocking certain proteins can prevent it.

Gender-specific analysis could improve treatment for childhood systemic lupus erythematosus.

Hair loss is common in lupus patients and can be permanent or reversible, depending on the type, with various treatments available.

Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.

The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Trichoscopy is useful for diagnosing and monitoring systemic lupus erythematosus, with certain hair and scalp changes indicating more active disease.

Topical clobetasol is recommended over mycophenolate mofetil for treating Lichen Planopilaris due to better safety and patient satisfaction.

Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.

Some skin medications can harm male fertility, but they don't seem to cause birth defects from father's exposure.

Effective treatments for severe alopecia areata are still lacking.

Cyclosporine combined with corticosteroids is more effective for severe alopecia areata than cyclosporine alone.

Ingesting Leucaena leucocephala caused hair loss and increased infant mortality in ringtailed lemurs.

Hair loss can indicate or worsen with systemic diseases, and treating the underlying condition is important.

Late onset SLE has different symptoms and antibody profiles compared to young onset SLE.

About 8% of people with systemic lupus erythematosus have chronic scarring alopecia, with certain symptoms and positive antibodies increasing the risk, while immunosuppressants may lower it.

Adalimumab is the most effective treatment for severe hidradenitis suppurativa, but more research is needed to improve treatment options.

Certain skin symptoms can help detect and manage systemic lupus.

Herbal hair oil made from herbs and coconut oil helps reduce dandruff and hair fall.

Tofacitinib successfully treated vitiligo in a patient with lupus without side effects.

SLE and DM can coexist but are rare and need careful evaluation.

Fever and rash can be early signs of lupus.