December 2023 in “Migration letters” This meta-analysis reviewed 25 studies and suggested that herbal interventions could improve reproductive health in women with PCOS, showing benefits across measures such as Body Mass Index, hirsutism, and insulin levels, although results were mixed for fasting glucose and FSH levels.
December 2025 in “ADMET & DMPK” This review synthesizes recent research to propose a precision framework for treating androgenetic alopecia and alopecia areata based on genetic insights and pathway biology, highlighting the roles of androgen-receptor signaling, immune dysregulation, and emerging therapies like regenerative medicine and AI-assisted diagnostics.
1 citations
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April 2009 in “Cochrane Database of Systematic Reviews” This protocol outlines a planned Cochrane Review assessing the effectiveness and safety of treatments for androgenic alopecia in women, reporting no new research findings.
December 2025 in “International Journal of Clinical Medical Research” This review explores the role of nutrition and probiotics in enhancing skin, hair, and nail health through gut microbiota, highlighting the potential of nutritional interventions for cosmetic benefits via the gut-skin axis.
January 2026 in “Microorganisms” In a DNFB-induced mouse model of atopic dermatitis, this study found that both topical and oral formulations of the probiotic Bifidobacterium animalis J12 improved AD symptoms through distinct mechanisms, with topical applications reducing local inflammation and oral administration enhancing gut microbiota and reducing systemic inflammation.
January 2024 in “International journal of homoeopathic sciences” This abstract discusses alopecia areata, highlighting its complex autoimmune pathogenesis involving immune cells and signaling molecules, and underscores the importance of accurate diagnosis and tailored management strategies, noting the need for further research to improve treatments.
1 citations
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November 2023 in “Life” Hyaluronic acid injections can improve mouth opening and quality of life in scleroderma patients.
24 citations
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July 2019 in “Cochrane library” This review found that oral methotrexate plus oral prednisone may improve disease activity or damage in juvenile active morphea compared to placebo plus prednisone, but adverse events may slightly increase.
5 citations
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May 2023 in “Frontiers in immunology” This review discusses how environmental factors like lifestyle, nutrition, and vitamin deficiencies may influence autoimmune diseases such as MS, SLE, and AA, highlighting associations with vitamin D levels and dietary interventions, but notes a lack of conclusive evidence for their roles in disease pathogenesis.
October 2025 in “Brazilian Journal of Hair Health” This narrative review identifies telogen effluvium as a growing concern linked to weight-loss interventions, such as GLP-1 receptor agonists and bariatric surgery, attributing hair loss to systemic and metabolic stress rather than permanent hair follicle damage.
281 citations
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January 2013 in “British Journal of Dermatology” Manage vitiligo with treatments, address emotions, and use camouflage techniques.
37 citations
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May 1999 in “Australasian Journal of Dermatology” This review discusses neutrophil-associated and infiltrative scarring alopecias, as well as promising new treatments, but reports no new clinical results.
35 citations
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October 2000 in “Dermatologic clinics” This review discusses the characteristics, impact, and management challenges of central centrifugal cicatricial alopecia and reports no new clinical findings, highlighting the need for further research and early detection strategies.
March 2026 in “Journal of Investigative Dermatology” Early diagnosis and tailored treatment are crucial to prevent permanent hair loss and support self-esteem in children with scarring alopecia.
February 2024 in “Benha Journal of Applied Sciences” This article reviews the current understanding, clinical features, diagnostic tests, and treatment options for androgenetic alopecia and reports no new clinical results.
January 2024 in “Frontiers in immunology” This review highlights the crucial role of histone modification in the pathogenesis and treatment of chronic inflammatory skin diseases, and explores therapeutic strategies targeting these epigenetic changes to improve management of conditions such as psoriasis and atopic dermatitis.
This review discusses the genetic differences between male and female pattern hair loss and highlights the uncertainty surrounding genetic factors in female pattern hair loss, but reports no clinical results.
2 citations
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April 2019 in “PubMed” This article reviews the chronic skin disorder hidradenitis suppurativa, discussing its symptoms, possible causes, and various treatment options, but reports no new clinical findings.
January 2025 in “Dermatology Review” This literature review reports significant advancements in dermatology from January 2018 to March 2024, highlighting progress in skin cancer detection, biologic therapies, wound healing, and pediatric dermatology, reflecting an evolving field that enhances clinical practice and patient care.
2 citations
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November 2018 in “Seminars in Cutaneous Medicine and Surgery” This source reviews treatments for female pattern hair loss and discusses the challenges in achieving effective regrowth, highlighting the need for combinations of topical, systemic, and interventional therapies.
March 2025 in “Dermatology” Systemic therapies improve nail psoriasis but have high side effects; more research is needed.
November 2024 in “International Society of Hair Restoration Surgery” This study investigated adverse events from low-dose systemic minoxidil in an older population with hair loss and found that 19% experienced mainly facial and body hypertrichosis, managed with interventions like dose reduction and diuretics; no serious adverse events occurred.
This case report details a 45-year-old woman with SLE who experienced severe leukopenia and hair loss attributed to azathioprine, suggesting the importance of recognizing these potential adverse effects for timely intervention.
December 2021 in “Journal of Rheumatic Diseases” In this case report, a 13-year-old girl with pediatric systemic lupus erythematosus experienced rare ischemic vaso-occlusive retinopathy as a first symptom, and early interventions improved her visual acuity and fever but did not fully restore vision.
October 2024 in “Cochrane library” This review examined evidence on non-systemic treatments for acne vulgaris and related skin complications, finding very low-certainty evidence that benzoyl peroxide may reduce lesion counts but may also increase the risk of minor adverse events, highlighting the need for higher-quality research for effective therapies.
1 citations
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December 2022 in “Sultan Qaboos University medical journal” In this study, a machine learning framework incorporating the CatBoost algorithm accurately predicted Systemic Lupus Erythematosus in Omani patients, suggesting potential for early clinical intervention.
December 2025 in “Cureus” In this case report, a 40-year-old woman with systemic lupus erythematosus developed calcinosis cutis, a rare complication characterized by calcified deposits in her legs, requiring surgical intervention and ongoing medical treatment due to infection.
August 2025 in “Galen Medical Journal” In this study, among 2,000 patients with alopecia universalis, mesotherapy combined with systemic treatments like BMI, JAK inhibitors, and adalimumab showed the highest success in hair regrowth, particularly for children, with the combination therapy group achieving a 42% positive response rate.
August 2023 in “Journal of The American Academy of Dermatology” This article discusses various treatments for primary cicatricial alopecia with a focus on early intervention to manage symptoms and improve hair density, but it reports no new clinical results.
February 2026 in “Frontiers in Immunology” This review highlights the role of the brain–gut–skin axis in systemic inflammatory skin conditions, revealing potential interventions like microbiome-directed treatments and integrative therapies, though emphasizes the need for more robust clinical validation.